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  • Description:
  • Involvement of actin cytoskeleton in MP formation. (A) PRP was incubated for 6 h with/without cytochalasin D (10 μM), latrunculin B (0.5 μM) or jasplakinolide (10 μM). (B) PRP was incubated for 6 h with cytochalasin D in the presence of integrin blockers (Fig. 4). (C) PRP was incubated with cytochalasin D plus wortmannin (1 μM). Data indicate MP coagulant activity as percentages of control PRP (incubation without drugs). ∗∗ P < 0.05 vs. control PRP,∗∗ P < 0.05 vs. vehicle (n = 3–4).
  • License:
  • Rights Managed
  • Rights Holder:
  • John Wiley & Sons, Inc.
  • License Rights Holder:
  • © 2015 Federation of European Biochemical Societies
  • Asset Type:
  • Image
  • Asset Subtype:
  • Chart/Graph
  • Image Orientation:
  • Portrait
  • Image Dimensions:
  • 300 x 737
  • Image File Size:
  • 54.2 KB
  • Creator:
  • Sandra Cauwenberghs, Marion A.H. Feijge, Alan G.S. Harper, Stewart O. Sage, Joyce Curvers, Johan W.M. Heemskerk
  • Credit:
  • Cauwenberghs, S., Feijge, M. A. H., Harper, A. G. S., Sage, S. O., Curvers, J., Heemskerk, J. W. M., Heemskerk, J. W., Bevers, E. M., Lindhout, T., Verhallen, P. F., Bevers, E. M., Comfurius, P., Zwaal, R. F., Fox, J. E., Bevers, E. M., Comfurius, P., Zwaal, R. F., Pasquet, J. M., Toti, F., Nurden, A. T., Dachary-Prigent, J., Fox, J. E., Austin, C. D., Reynolds, C. C., Steffen, P. K., Freyssinet, J. M., Hugel, B., Martinez, M. C., Kunzelmann, C., Freyssinet, J. M., Arias-Salgado, E. G., Lizano, S., Sarkar, S., Brugge, J. S., Ginsberg, M. H., Shattil, S. J., Ginsberg, M. H., Partridge, A., Shattil, S. J., Falet, H., Chang, G., Brohard-Bohn, B., Rendu, F., Hartwig, J. H., Fox, J. E., Taylor, R. G., Taffarel, M., Boyles, J. K., Goll, D. E., Schoenwaelder, S. M., Jackson, S. P., Yuan, Y., Teasdale, M. S., Salem, H. H., Mitchell, C. A., Curvers, J., van Pampus, E. C., Feijge, M. A., Rombout-Sestrienkova, E., Giesen, P. L., Heemskerk, J. W., Cauwenberghs, S., Feijge, M. A., Hageman, G., Hoylaerts, M., Akkerman, J. W., Curvers, J., Heemskerk, J. W., Feijge, M. A., van Pampus, E. C., Lacabaratz-Porret, C., Hamulyak, K., Levy-Toledano, S., Enouf, J., Heemskerk, J. W., Lisman, T., Adelmeijer, J., Cauwenberghs, S., Van Pampus, E. C., Heemskerk, J. W., De Groot, P. G., Siljander, P., Farndale, R. W., Feijge, M. A., Comfurius, P., Kos, S., Bevers, E. M., Heemskerk, J. W., Vanschoonbeek, K., Feijge, M. A., Van Kampen, R. J., Kenis, H., Hemker, H. C., Giesen, P. L., Heemskerk, J. W., Lecut, C., Schoolmeester, A., Kuijpers, M. J., Broers, J. L., van Zandvoort, M. A., Vanhoorelbeke, K., Deckmyn, H., Jandrot-Perrus, M., Heemskerk, J. W., Heemskerk, J. W., Kuijpers, M. J., Munnix, I. C., Siljander, P. R., Pasquet, J. M., Dachary-Prigent, J., Nurden, A. T., Topol, E. J., Byzova, T. V., Plow, E. F., Calderwood, D. A., Shattil, S. J., Ginsberg, M. H., Rosado, J. A., Jenner, S., Sage, S. O., Shattil, S. J., Wiedmer, T., Shattil, S. J., Cunningham, M., Sims, P. J., Gemmell, C. H., Sefton, M. V., Yeo, E. L., Holme, P. A., Solum, N. O., Brosstad, F., Egberg, N., Lindahl, T. L., Matzdorff, A. C., Kuhnel, G., Kemkes-Matthes, B., Pralle, H., Voss, R., Fareed, J., Fox, J. E., Austin, C. D., Boyles, J. K., Steffen, P. K., Bennett, J. S., Andrews, R. K., Gardiner, E. E., Shen, Y., Berndt, M. C., Reverter, J. C., Beguin, S., Kessels, H., Kumar, R., Hemker, H. C., & Coller, B. S. (2006). Shedding of procoagulant microparticles from unstimulated platelets by integrin‐mediated destabilization of actin cytoskeleton. FEBS Letters, 580(22), 5313-5320. https://doi.org/10.1016/j.febslet.2006.08.
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Sandra Cauwenberghs, Marion A.H. Feijge, Alan G.S. Harper, Stewart O. Sage, Joyce Curvers, Johan W.M. Heemskerk
  • Article Copyright Year:
  • 2006
  • Publication Volume:
  • 580
  • Publication Issue:
  • 22
  • Publication Date:
  • 10/02/2006
  • DOI:

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