Asset Details

  • Description:
  • JANEX‐1 inhibits lipopolysaccharide (LPS)‐induced inflammatory mediator release by colonic epithelial cells. Monolayers of colonic epithelial cell line, HT29, were treated with JANEX‐1 (3, 10, and 30 μm) for 1 hr prior to LPS (5 μg/mL) challenge. After 6 h, levels of PGE2 (a) and interleukin‐8 (b) were measured in cell‐free supernatants by enzyme‐linked immunosorbent assay. Data are expressed as mean ± S.E.M. of three to five independent experiments. *P < 0.05 compared to control.
  • License:
  • Rights Managed
  • Rights Holder:
  • John Wiley & Sons, Inc.
  • License Rights Holder:
  • Asset Type:
  • Image
  • Asset Subtype:
  • Chart/Graph
  • Image Orientation:
  • Portrait
  • Image Dimensions:
  • 400 x 763
  • Image File Size:
  • 18 KB
  • Creator:
  • Osmond J. D’Cruz, Fatih M. Uckun
  • Credit:
  • D’Cruz, O. J., & Uckun, F. M. (2007). Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1. American Journal of Reproductive Immunology, 58(2), 75-97. https://doi.org/10.1111/j.1600-0897.2007.00502.x.
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Osmond J. D’Cruz, Fatih M. Uckun
  • Article Copyright Year:
  • 2007
  • Publication Volume:
  • 58
  • Publication Issue:
  • 2
  • Publication Date:
  • 08/01/2007
  • DOI:
  • https://doi.org/10.1111/j.1600-0897.2007.00502.x

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