Asset Details
- Identifier:
- AJI_502_f5
- Description:
- Anti‐inflammatory effects of a 7‐day treatment with JANEX‐1 in a murine peritonitis model. C3H‐FeJ mice were treated for seven consecutive days with i.p. injections of 2 mg/kg or 4 mg/kg JANEX‐1. Mice were then challenged with an i.p. injection of paraffin oil as an peritoneal irritant. Inflammatory macrophages were harvested by peritoneal lavage 3 days after the injection of paraffin oil and cultured in the presence or absence of 10 ng/mL or 100 ng/mL lipopolysaccharide (LPS). (a) The numbers of inflammatory macrophages in peritoneal lavage samples. (b) The effect of JANEX‐1 treatment on LPS‐induced tumor necrosis factor‐α production by peritoneal macrophages from the treated mice. (c) The effect of JANEX‐1 treatment on LPS‐induced nitric oxide production by peritoneal macrophages from the treated mice. Each data point depicts the mean ± S.E. values from five mice.
- License:
- Rights Managed
- Rights Holder:
- John Wiley & Sons, Inc.
- License Rights Holder:
- Asset Type:
- Image
- Asset Subtype:
- Chart/Graph
- Image Orientation:
- Portrait
- Image Dimensions:
- 400 x 1110
- Image File Size:
- 34.9 KB
- Creator:
- Osmond J. D’Cruz, Fatih M. Uckun
- Credit:
- D’Cruz, O. J., & Uckun, F. M. (2007). Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1. American Journal of Reproductive Immunology, 58(2), 75-97. https://doi.org/10.1111/j.1600-0897.2007.00502.x.
- Collection:
- Keywords:
- Restrictions:
- Property Release:
- No
- Model Release:
- No
- Purchasable:
- Yes
- Sensitive Materials:
- No
- Article Authors:
- Osmond J. D’Cruz, Fatih M. Uckun
- Article Copyright Year:
- 2007
- Publication Title:
- American Journal of Reproductive Immunology
- Publication Volume:
- 58
- Publication Issue:
- 2
- Publication Date:
- 08/01/2007
- DOI:
- https://doi.org/10.1111/j.1600-0897.2007.00502.x
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