Asset Details

  • Description:
  • Mibefradil only dilates SEAs. (A) Typical recording of a pressurized SEA showing that mibefradil induces vasodilation in a concentration‐dependent manor. (B) Summary means ± SE (n = 7) for mibefradil‐induced dilation in SEAs with 19 ± 4% myogenic tone. Emax = 0.74 ± 0.08; Log EC50 = −6.9 ± 0.7 (0.13 μmol/L); Hill‐slope = 0.8 ± 0.2 by nonlinear curve fitting (See Methods).
  • License:
  • Rights Managed
  • Rights Holder:
  • John Wiley & Sons, Inc.
  • License Rights Holder:
  • © 2017 John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics
  • Asset Type:
  • Image
  • Asset Subtype:
  • Chart/Graph
  • Image Orientation:
  • Landscape
  • Image Dimensions:
  • 2128 x 1952
  • Image File Size:
  • 332 KB
  • Creator:
  • Brendan Mullan, Jessica Pettis, William F. Jackson
  • Credit:
  • Mullan, B., Pettis, J., & Jackson, W. F. (2017). T‐type voltage‐gated Ca2+ channels do not contribute to the negative feedback regulation of myogenic tone in murine superior epigastric arteries. Pharmacology Research & Perspectives, 5(3), https://doi.org/10.1002/prp2.
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Brendan Mullan, Jessica Pettis, William F. Jackson
  • Article Copyright Year:
  • 2017
  • Publication Volume:
  • 5
  • Publication Issue:
  • 3
  • Publication Date:
  • 06/01/2017
  • DOI:
  • https://doi.org/10.1002/prp2

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