Asset Details

  • Description:
  • Effects of hypoxia‐inducible factor‐2α (HIF‐2α) and stearoyl–CoA desaturase‐1 (SCD1) on cell migration. Renal carcinoma 786‐0 cells infected with shRNA were seeded at 1 × 105 into a Transwell insert and cultured for 24 h for cell migration. Photographs of the migrated cells were taken from five fields. Representative photographs for each group are shown and the average cell numbers per field were calculated. Panel 1, scrambled sequences for SCD1 and HIF‐2α (Ctrl); panel 2, siRNA against HIF‐2α (shHIF‐2α) + scrambled sequences for siRNA against SCD1 (shSCD1); panel 3, shSCD1 + scrambled sequences for shHIF‐2α; panel 4, shSCD1 + shHIF‐2α. *P < 0.05 for shSCD1 or siRNA against HIF‐2α (shHIF‐2α) versus Ctrl; **P < 0.05 for double shRNA versus shSCD1 or shHIF‐2α.
  • License:
  • Rights Managed
  • Rights Holder:
  • John Wiley & Sons, Inc.
  • License Rights Holder:
  • © 2013 Japanese Cancer Association
  • Asset Type:
  • Image
  • Asset Subtype:
  • Illustration
  • Image Orientation:
  • Landscape
  • Image Dimensions:
  • x
  • Image File Size:
  • 137 KB
  • Creator:
  • Yujian Zhang, Hui Wang, Jin Zhang, Jianwei Lv, Yiran Huang
  • Credit:
  • Zhang, Y., Wang, H., Zhang, J., Lv, J., & Huang, Y. (2013). Positive feedback loop and synergistic effects between hypoxia‐inducible factor‐2α and stearoyl–CoA desaturase‐1 promote tumorigenesis in clear cell renal cell carcinoma. Cancer Science, 104(4), 416-422..
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Yujian Zhang, Hui Wang, Jin Zhang, Jianwei Lv, Yiran Huang
  • Article Copyright Year:
  • 2013
  • Publication Volume:
  • 104
  • Publication Issue:
  • 4
  • Publication Date:
  • 04/01/2013
  • DOI:

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