Asset Details
- Identifier:
- cncy22187-fig-0005
- Description:
- (A‐C) This mediastinal lymph node fine‐needle aspiration (FNA) (patient 10, sample 11) was originally diagnosed as poorly differentiated neuroendocrine carcinoma. (A) A ThinPrep slide shows blast‐like cells with distinct nucleoli and smaller, benign background lymphocytes (Papanicolaou stain, original magnification ×600). (B) The corresponding cell block shows a compact, squamoid morule highlighted by nuclear β‐catenin stain (inset). (C) A corresponding pancreatic resection shows large sheets of monotonous, small, round‐to‐elongated blue cells with diffuse nuclear β‐catenin staining (inset) and immature, hypercellular stroma (H&E stain, original magnification ×200). (D) A pancreatic FNA biopsy from case 1 that was misdiagnosed as neuroendocrine neoplasm shows spindled‐to‐oval, small, round cells with nuclear molding resembling small‐cell carcinoma (Papanicolaou stain, original magnification ×200). (E) A 2‐cell population of smaller blast‐like cells is shown along with a single squamoid cell (arrow) with abundant, dense cytoplasm and a large nucleus (Diff‐Quik stain, original magnification ×200). (F‐I) Squamoid morules ranged from (F) ill‐defined, pale‐pink clusters (Diff‐Quik stain, original magnification ×200) to (G) tight, whorled units of epithelioid cells with pale cytoplasm and syncytial arrangement (Papanicolaou stain, original magnification ×200). (H) A corresponding cell block and (I) pancreatic resection show similar tight, eosinophilic, squamoid morules surrounded by monotonous, blast‐like blue cells with intervening cellular stroma (H&E stain, original magnification ×200).
- License:
- Rights Managed
- Rights Holder:
- John Wiley & Sons, Inc.
- License Rights Holder:
- © 2019 American Cancer Society
- Asset Type:
- Image
- Asset Subtype:
- Figure
- Image Orientation:
- Landscape
- Image Dimensions:
- 2079 x 1106
- Image File Size:
- 3.39 MB
- Creator:
- Michelle D. Reid, MD, Shristi Bhattarai, Rondell P. Graham, MBBS, Burcin Pehlivanoglu, MD, Carlie S. Sigel, MD, Jiaqi Shi, MD, Anjali Saqi, MD, Maryam Shirazi, MD, Yue Xue, MD, Olca Basturk, MD, Volkan Adsay, MD
- Credit:
- Reid, M. D., Bhattarai, S., Graham, R. P., Pehlivanoglu, B., Sigel, C. S., Shi, J., Saqi, A., Shirazi, M., Xue, Y., Basturk, O., & Adsay, V. (2019). Pancreatoblastoma: Cytologic and histologic analysis of 12 adult cases reveals helpful criteria in their diagnosis and distinction from common mimics. Cancer Cytopathology, 127(11), 708-719..
- Collection:
- Keywords:
- Restrictions:
- Property Release:
- No
- Model Release:
- No
- Purchasable:
- Yes
- Sensitive Materials:
- No
- Article Authors:
- Michelle D. Reid, MD, Shristi Bhattarai, Rondell P. Graham, MBBS, Burcin Pehlivanoglu, MD, Carlie S. Sigel, MD, Jiaqi Shi, MD, Anjali Saqi, MD, Maryam Shirazi, MD, Yue Xue, MD, Olca Basturk, MD, Volkan Adsay, MD
- Article Copyright Year:
- 2019
- Publication Title:
- Cancer Cytopathology
- Publication Volume:
- 127
- Publication Issue:
- 11
- Publication Date:
- 11/01/2019
- DOI:
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