Asset Details

  • Description:
  • Laser test ablations were successful in all patients and showed complete regression within the ablated areas, whereas the untreated sites were still affected. In patients 1, 2, and 3, complementary laser removal of control lesions led to excellent results (Figure 2), and the treated areas showed no recurrence during follow-up (Table 1). No adverse effects (eg, wound infection, hyperpigmentation, or scarring), other than slight hypopigmentation of the cubital fossa and the popliteal cavity in patient 2, and a few atrophic hypopigmented spots after deeper ablation in patient 1, occurred during the period of observation. It is noteworthy that even the plaquelike areas on the ventral aspect of the neck of patient 2 could be cleared completely without any adverse effects even though this region is at high risk for scar formation (Figure 2, right). Both patients with DD also experienced complete relief from itching. It was interesting to observe that ablation of solitary follicular hyperkeratotic papules in the patients with DD resulted in a "wicklike" situs represented by a small prominent keratotic core in the center of the lesion and needed additional focused single pulses for removal. This "wick phenomenon" is likely to be caused by reduced water content (absorbing target) and consequently by less effective ablation within the central hyperkeratotic follicular area.
  • License:
  • Rights Managed
  • Rights Holder:
  • JAMA
  • License Rights Holder:
  • Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
  • Asset Type:
  • Image
  • Asset Subtype:
  • Photo
  • Image Orientation:
  • Landscape
  • Image Dimensions:
  • 590 x 384
  • Image File Size:
  • 77.5 KB
  • Creator:
  • Christian Beier MD, Roland Kaufmann MD
  • Credit:
  • Beier, C., & Kaufmann, R. (1999). Efficacy of Erbium:YAG Laser Ablation in Darier Disease and Hailey-Hailey Disease. Arch Dermatol, 135(4), 423-427. https://doi.org/10.1001/archderm.135.4.423.
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Christian Beier MD, Roland Kaufmann MD
  • Article Copyright Year:
  • 1999
  • Publication Volume:
  • 135
  • Publication Issue:
  • 4
  • Publication Date:
  • 04/01/1999
  • DOI:
  • https://doi.org/10.1001/archderm.135.4.423

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