Asset Details

  • Description:
  • Indels in myo7aa target sites of CRISPR/Cas9‐generated mariner mutants. (A) The illustration of structure of functional domains of Myo7aa. The two blue lines indicate the target sites of used sgRNAs. (B) DNA sequences of exon 3 of myo7aa in control (WT) and of both alleles of mutant 1 (Mut 1‐1 and Mut 1‐2), and mutant 2 (Mut 2‐1 and Mut 2‐2). The sequences highlighted in green show the target sites of two sgRNAs. Small dashed lines represent the deleted nucleotides. The red nucleotides represent the inserted nucleotides. The number on the right side of each allele represents the number of repeats of that particular allele. The sequencing trace data were shown in chromatograms. (C) Amino‐acid sequences of Myo7aa in control (WT) and mutant alleles. The sequences highlighted in yellow show the alternated amino acids in the mutant alleles. The black asterisks indicate the position of stop codon. The red X's indicate the deleted amino acids in the mutant alleles.
  • License:
  • Rights Managed
  • Rights Holder:
  • John Wiley & Sons, Inc.
  • License Rights Holder:
  • © 2020 Wiley Periodicals, Inc.
  • Asset Type:
  • Image
  • Asset Subtype:
  • Figure
  • Image Orientation:
  • Portrait
  • Image Dimensions:
  • 2128 x 2165
  • Image File Size:
  • 2.23 MB
  • Creator:
  • Bing Zou, Alexandra A. Desmidt, Rahul Mittal, Denise Yan, Micheal Richmond, Mustafa Tekin, Xue Zhong Liu, Zhongmin Lu
  • Credit:
  • Zou, B., Desmidt, A. A., Mittal, R., Yan, D., Richmond, M., Tekin, M., Liu, X. Z., & Lu, Z. (2020). The Generation of Zebrafish Mariner Model Using the CRISPR/Cas9 System. The Anatomical Record, 303(3), 556-562..
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Bing Zou, Alexandra A. Desmidt, Rahul Mittal, Denise Yan, Micheal Richmond, Mustafa Tekin, Xue Zhong Liu, Zhongmin Lu
  • Article Copyright Year:
  • 2020
  • Publication Volume:
  • 303
  • Publication Issue:
  • 3
  • Publication Date:
  • 03/01/2020
  • DOI:

Click on image to enlarge

Would you like to download this asset? Tell us more and we can generate a quote, license and downloadable file.

Add to Cart