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  • Description:
  • Effect of carotid stiffness, induced by periarterial application of CaCl2, on oxidative stress, assessed by superoxide anion production in the hippocampus. A, Representative sections of different regions of the hippocampus (×40 magnification), stained with DHE, in mice with carotid arteries submitted to application of 0.3 mol/L CaCl2 or 0.9% NaCl (control). B, Superoxide anion production assessed by DHE fluorescence (relative fluorescence units) in CA1, CA3, and DG regions of hippocampus for different concentrations of CaCl2 or 0.9% NaCl (control). C, Superoxide anion production assessed by DHE fluorescence (relative fluorescence units) in right or left hemisphere of the hippocampus for different concentrations of CaCl2 or 0.9% NaCl (n=3; ***P<0.001 vs 0.9% NaCl, **P<0.01 vs 0.9% NaCl, *P<0.05 vs 0.9% NaCl). CaCl2 indicates calcium chloride; NaCl, sodium chloride; DHE, dihydroethidium; CA1 and CA3, cornu ammonis 1 and 3; DG, dentate gyrus.
  • License:
  • CC-BY-NC
  • Rights Holder:
  • Rights Managed by John Wiley & Sons
  • License Rights Holder:
  • Copyright © 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley‐Blackwell
  • Asset Type:
  • Image
  • Asset Subtype:
  • Photo
  • Image Orientation:
  • Portrait
  • Image Dimensions:
  • 978 x 1142
  • Image File Size:
  • 495 KB
  • Creator:
  • Nataliya Sadekova, MSc, Diane Vallerand, BSc, Edgar Guevara, MSc, Frédéric Lesage, PhD, Hélène Girouard, PhD
  • Credit:
  • Rabkin, S., Triantafyllidi, H., Arvaniti, C., Lekakis, J., Ikonomidis, I., Siafakas, N., Tzortzis, S., Trivilou, P., Zerva, L., Stamboulis, E., Kremastinos, D., Pase, M., Herbert, A., Grima, N., Pipingas, A., O'Rourke, M., Scuteri, A., Tesauro, M., Appolloni, S., Preziosi, F., Brancati, A., Volpe, M., Watson, N., Sutton‐Tyrrell, K., Rosano, C., Boudreau, R., Hardy, S., Simonsick, E., Najjar, S., Launer, L., Yaffe, K., Atkinson, H., Satterfield, S., Newman, A., Waldstein, S., Rice, S., Thayer, J., Najjar, S., Scuteri, A., Zonderman, A., Safar, M., Frohlich, E., Niederhoffer, N., Lartaud‐Idjouadiene, I., Giummelly, P., Duvivier, C., Peslin, R., Atkinson, J., Essalihi, R., Dao, H., Yamaguchi, N., Moreau, P., Atkinson, J., Briones, T., Darwish, H., Ferland, G., Angouras, D., Sokolis, D., Dosios, T., Kostomitsopoulos, N., Boudoulas, H., Skalkeas, G., Karayannacos, P., Saeki, A., Recchia, F., Kass, D., Demer, L., Tintut, Y., Wagenseil, J., Mecham, R., Marque, V., Kieffer, P., Gayraud, B., Lartaud‐Idjouadiene, I., Ramirez, F., Atkinson, J., Drouin, A., Bolduc, V., Thorin‐Trescases, N., Belanger, E., Fernandes, P., Baraghis, E., Lesage, F., Gillis, M., Villeneuve, L., Hamel, E., Ferland, G., Thorin, E., Bolduc, V., Drouin, A., Gillis, M., Duquette, N., Thorin‐Trescases, N., Frayne‐Robillard, I., Des Rosiers, C., Tardif, J., Thorin, E., Gertz, S., Kurgan, A., Eisenberg, D., Basalyga, D., Simionescu, D., Xiong, W., Baxter, B., Starcher, B., Vyavahare, N., Chiou, A., Chiu, B., Pearce, W., Ikonomidis, J., Gibson, W., Gardner, J., Sweterlitsch, S., Thompson, R., Mukherjee, R., Spinale, F., Tieu, B., Lee, C., Sun, H., Lejeune, W., Recinos, A., Ju, X., Spratt, H., Guo, D., Milewicz, D., Tilton, R., Braser, A., Ahearn, J., Fischer, M., Croix, D., Goerg, S., Ma, M., Xia, J., Zhou, X., Howard, R., Rothstein, T., Carroll, M., Amin, M., Le, V., Wagenseil, J., Flamant, M., Placier, S., Dubroca, C., Esposito, B., Lopes, I., Chatziantoniou, C., Tedgui, A., Dussaule, J., Ledoux, S., Baraghis, E., Bolduc, V., Lefebvre, J., Srinivasan, V., Boudoux, C., Thorin, E., Lesage, F., Schmued, L., Hopkins, K., Safar, M., Levy, B., Struijker‐Boudier, H., Xu, C., Zarins, C., Pannaraj, P., Bassiouny, H., Glagov, S., Zieman, S., Melenovsky, V., Kass, D., Jurasic, M., Josef‐Golubic, S., Sarac, R., Lovrencic‐Huzjan, A., Demarin, V., Horvath, T., Pinter, A., Kollai, M., Tomimatsu, T., Fujime, M., Kanayama, T., Mimura, K., Koyama, S., Kanagawa, T., Kimura, T., Kocyigit, I., Kaya, M., Orscelik, O., Kaya, C., Akpek, M., Zengin, H., Sipahioglu, M., Unal, A., Yilmaz, M., Tokgoz, B., Oymak, O., Axelsson, J., Michas, F., Manios, E., Stamatelopoulos, K., Koroboki, E., Toumanidis, S., Panerai, R., Zakopoulos, N., Kaess, B., Rong, J., Larson, M., Hamburg, N., Vita, J., Levy, D., Benjamin, E., Vasan, R., Mitchell, G., Mitchell, G., Buchem, M., Sigurdsson, S., Gotal, J., Jonsdottir, M., Kjartansson, O., Garcia, M., Aspelund, T., Harris, T., Gudnason, V., Launer, L., Mitchell, G., Li, M., Scott, D., Shandas, R., Stenmark, K., Tan, W., Wåhlin, A., Harrison, D., Griendling, K., Landmesser, U., Hornig, B., Drexler, H., Silacci, P., Desgeorges, A., Mazzolai, L., Chambaz, C., Hayoz, D., Capogna, M., Soros, P., Whitehead, S., Spence, J., Hachinski, V., Alsop, D., Casement, M., Bazelaire, C., Fong, T., Press, D., Wang, X., & Michaelis, E. (2013). Carotid Calcification in Mice: A New Model to Study the Effects of Arterial Stiffness on the Brain. Journal of the American Heart Association, 2(3), n/a-n/a. https://doi.org/10.1161/JAHA.113.
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  • This image was published under the terms of the Creative Commons Attribution-NonCommercial License, (CC-BY-NC) which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. You may purchase a high resolution image file if your request is non-commercial.
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Nataliya Sadekova, MSc, Diane Vallerand, BSc, Edgar Guevara, MSc, Frédéric Lesage, PhD, Hélène Girouard, PhD
  • Article Copyright Year:
  • 2013
  • Publication Volume:
  • 2
  • Publication Issue:
  • 3
  • Publication Date:
  • 06/01/2013
  • DOI:

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