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Description Table of fitted values for estimated (upper part) and assigned (lower part) parameter values in a homeostatic system
Article Title: Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach
Publication Title: STEM CELLS -
Description Model setup and parameter estimation. (A): Sketch of the mathematical model setup. Repopulating hematopoietic stem cells (rpHSCs; red) are able to proliferate with an effective proliferation rate...
Article Title: Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach
Publication Title: STEM CELLS -
Description Hematopoietic stress response in a young mouse. Time courses, given in cell frequency relative to steady state cell numbers, illustrate the dynamic system response to targeted depletion (dashed...
Article Title: Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach
Publication Title: STEM CELLS -
Description Hematopoietic aging. (A): Measured cell frequencies in long‐term hematopoietic stem cell (HSC), short‐term HSC, and LMPP compartments for young (10–12 weeks), middle‐aged (40–54 weeks), and old...
Article Title: Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach
Publication Title: STEM CELLS -
Description Hematopoietic stress response in an old mouse. Time courses, given in cell frequency relative to steady state cell numbers, illustrate the dynamic system response to targeted depletion (dashed...
Article Title: Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach
Publication Title: STEM CELLS