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Description MRL/+/rpl mice are less sensitive to concanavalin A (Con A)‐induced hepatitis. MRL/+ and MRL/+/rpl mice were injected with the indicated dose of Con A in the tail vein. Plasma transaminase levels...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology -
Description The development of hepatitis in MRL/lpr/rpl mice was mediated by CD4+ and CD8+ T cells. MRL/+, MRL/lpr and MRL/lpr/rpl mice were pretreated with monoclonal anti‐CD4 (GK1·5) or anti‐CD8 (53–6·72) or...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology -
Description Hepatitis in MRL/lpr/rpl mice was not mediated by interleukin‐4 (IL‐4). MRL/+, MRL/lpr and MRL/lpr/rpl mice were injected in the tail vein with the indicated dose of concanavalin A (Con A). Serum...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology -
Description Vα14 NKT cells are absent in MRL/lpr/rpl mice. Hepatic mononuclear cells and splenocytes from MRL mice were stained with murine CD1d:Ig‐α‐galactosylceramide and monoclonal anti‐T‐cell receptor...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology -
Description Hepatitis in MRL/lpr/rpl mice was mediated by 2B4+ T cells. MRL/+ and MRL/lpr/rpl mice were pretreated by hydrodynamic injection of the indicated plasmids and injected with the indicated dose of...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology -
Description Histological analysis of the liver of MRL mice with induced hepatitis. Microscopic images of the livers of MRL/+ (a), MRL/lpr (b) and MRL/lpr/rpl (c) concanavalin A (Con A)‐injected mice after...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology -
Description MRL/lpr/rpl mice are susceptible to concanavalin A (Con A)‐induced hepatitis. MRL/+, MRL/lpr and MRL/lpr/rpl mice were injected with the indicated dose of Con A into the tail vein. Plasma...
Article Title: Role of 2B4‐mediated signals in the pathogenesis of a murine hepatitis model independent of Fas and Vα14 NKT cells
Publication Title: Immunology