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Description Summary of Anti‐inflammatory Activity of JANEX‐1 in Preclinical Models of Inflammation
Article Title: Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1
Publication Title: American Journal of Reproductive Immunology -
Description JANEX‐1 inhibits lipopolysaccharide (LPS)‐induced inflammatory mediator release by colonic epithelial cells. Monolayers of colonic epithelial cell line, HT29, were treated with JANEX‐1 (3, 10, and...
Article Title: Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1
Publication Title: American Journal of Reproductive Immunology -
Description Anti‐inflammatory effects of a 7‐day treatment with JANEX‐1 in a murine peritonitis model. C3H‐FeJ mice were treated for seven consecutive days with i.p. injections of 2 mg/kg or 4 mg/kg JANEX‐1....
Article Title: Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1
Publication Title: American Journal of Reproductive Immunology -
Description Structure and activity of JANEX‐1.
Article Title: Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1
Publication Title: American Journal of Reproductive Immunology -
Description JANEX‐1 inhibits ultraviolet‐B (UVB)‐induced PGE2 synthesis. HaCaT cells were either irradiated with UVB (25 mJ/cm2) or sham irradiated. JANEX‐1 was added 1 hr prior to irradiation and after UVB...
Article Title: Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1
Publication Title: American Journal of Reproductive Immunology -
Description JANEX‐1 inhibits lipopolysaccharide (LPS)‐induced tumor necrosis factor (TNF)‐α and nitric oxide (NO) production by macrophages. Murine peritoneal macrophages (a) or RAW 264.7 cells (b) were...
Article Title: Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1
Publication Title: American Journal of Reproductive Immunology