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Description Expression of N‐CoR interaction domain fragments restores D3‐induced differentiation of leukemia cells. (A) D3‐induced differentiation of NB4 or NB4R4 cells, carrying an empty GFP vector (V) or...
Article Title: Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
Publication Title: The EMBO Journal -
Description Expression of N‐CoR interaction domain fragments restores RA‐induced differentiation in RA‐resistant leukemia cells. (A) RA‐induced differentiation (+) of the indicated cell lines, carrying an...
Article Title: Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
Publication Title: The EMBO Journal -
Description Expression of interaction domain protein fragments induces proteosomal degradation of the PML/RARα fusion protein. (A) Western blotting with anti‐RARα‐F or anti‐AML1. P/R and A/E stand for the...
Article Title: Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
Publication Title: The EMBO Journal -
Description Expression of the N‐CoR fragments disrupts the fusion protein/corepressor complexes on fusion protein target genes. (A) Western blotting of cell lysates stably expressing the indicated N‐CoR...
Article Title: Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
Publication Title: The EMBO Journal -
Description TAT PTD‐mediated transduction of IDC, IDN or RD3 restores differentiation of leukemia cells. (A) Western blotting from lysates of the indicated cells transduced with TAT‐IDC, TAT‐IDN, TAT‐M10 or...
Article Title: Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
Publication Title: The EMBO Journal -
Description Effects of the different interaction domain protein fragments on the expression of corepressor and fusion protein target genes. (A) Interaction regions of the N‐CoR protein and the PML/RARα and...
Article Title: Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
Publication Title: The EMBO Journal