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Description A typical S-EMG time course is shown in Figure 4.
Article Title: Creatine Therapy in Myophosphorylase Deficiency (McArdle Disease)
Publication Title: Arch Neurol -
Description In the emergency department she did not respond to painful stimuli. Vital signs, electrocardiographic evidence, and laboratory findings, including arterial blood gas values, were normal. Neurologic...
Article Title: Diffusion-Weighted Imaging Abnormalities in Wernicke Encephalopathy
Publication Title: Arch Neurol -
Description Immunoblot analysis showed that the antibodies against AQP4, dystrophin, and -spectrin reacted with 31-, 427-, and 270-kd protein extracts, respectively, of normal and disease control human...
Article Title: Reduced Aquaporin 4 Expression in the Muscle Plasma Membrane of Patients With Duchenne Muscular Dystrophy
Publication Title: Arch Neurol -
Description Cerebrospinal fluid -amyloid(1-42) levels were significantly (P.001) decreased in the AD group (709304 pg/mL) compared with the control group (1678436 pg/mL). The individual values are shown in...
Article Title: Cerebrospinal Fluid -Amyloid(1-42) in Alzheimer Disease
Publication Title: Arch Neurol -
Description Figure 2 shows the estimates of change in cognitive performance for persons within diagnostic subgroups. Substantial cognitive decline is evident in persons with Alzheimer disease diagnosed at...
Article Title: Change in Cognitive Function in Older Persons From a Community Population
Publication Title: Arch Neurol -
Description Two novel disease-causing mutations were found in 3 affected individuals of family 4 (Figure 4A). V56E consists in a TA transversion at position 268 in the complementary DNA that creates a new...
Article Title: Molecular Findings in Familial Parkinson Disease in Spain
Publication Title: Arch Neurol -
Description Blood was centrifuged with Ficoll-Paque (Amersham Pharmacia Biotech Italia, Milan, Italy) at 400g for 30 minutes at room temperature. Buffy coats of mononuclear cells were spun at 800g for 10...
Article Title: T-Cell Interferon Gamma Receptor Binding in Interferon Beta-1bTreated Patients With Multiple Sclerosis
Publication Title: Arch Neurol -
Description Cross-classification of dependence level with visit demonstrated that rankings reflected progressively increased dependency with time. At baseline, most patients were ranked at level 2. However, by...
Article Title: Longitudinal Assessment of Patient Dependence in Alzheimer Disease
Publication Title: Arch Neurol -
Description Survival curves for a patient to remain in the probable MS group or experience an additional relapse over time are presented in Figure 3. Survival distributions between groups in relation to...
Article Title: Multiple SclerosisFrom Probable to Definite Diagnosis
Publication Title: Arch Neurol -
Description There was considerable variance in the neuronal count in hippocampal field CA1 within each group, probably owing to the difficulty in identifying the boundaries of CA1. There was one outlying case...
Article Title: Neuron Number in the Entorhinal Cortex and CA1 in Preclinical Alzheimer Disease
Publication Title: Arch Neurol -
Description A series of orthogonal T1-weighted images for localization were obtained, with the transaxial plane approximately parallel to the long axis of the hippocampus. The preselected region of excitation...
Article Title: Ictal Fear in Temporal Lobe Epilepsy
Publication Title: Arch Neurol -
Description The most consistent findings were symmetric, hyperintense signal changes in the basal ganglia on images with long repetition times. In 109 (67.3%) of 162 CJD patients with sporadic CJD, MRIs showed...
Article Title: Magnetic Resonance Imaging in the Clinical Diagnosis of Creutzfeldt-Jakob Disease
Publication Title: Arch Neurol -
Description Table 2. Survival Analyses Stratified by Presence of Clinical Characteristics, Olmsted County, Minnesota, 1976-2000*
Article Title: Survival Study of Parkinson Disease in Olmsted County, Minnesota
Publication Title: Arch Neurol -
Description Spectroscopic VOI was prescribed using the T2 images, and was centered on the left and right posterior limb of the internal capsule in turn (Figure 1). Placement of the left and right voxels was...
Article Title: Axonal Injury or Loss in the Internal Capsule and Motor Impairment in Multiple Sclerosis
Publication Title: Arch Neurol -
Description Figure 1 summarizes the results of the ratings of MTA, periventricular hyperintensities, and white matter hyperintensities for all subjects with dementia according to the absence of an APOE 4...
Article Title: Apolipoprotein E 4 Allele, Temporal Lobe Atrophy, and White Matter Lesions in Late-Life Dementias
Publication Title: Arch Neurol -
Description Magnetic resonance imaging of the cervical spine revealed a cord lesion at the level of the fifth through sixth cervical vertebrae (Figure 2), which was predominantly left sided on sequential...
Article Title: Traumatic Brown-SquardPlus Syndrome
Publication Title: Arch Neurol -
Description In case 2, the diffusion-weighted image after 6 weeks revealed increased signal in the right frontal and temporoparietal areas (Figure 3, top). Although no abnormalities were detected in FLAIR...
Article Title: Diffusion-Weighted Magnetic Resonance Imaging in Probable Creutzfeldt-Jakob Disease
Publication Title: Arch Neurol -
Description The distribution of the composite premorbid reading measure was approximately normal (Figure 1). Scores ranged from 0 to 21 (mean [SD] score, 8.00 [3.96]), with higher scores indicating more...
Article Title: Premorbid Reading Activity and Patterns of Cognitive Decline in Alzheimer Disease
Publication Title: Arch Neurol -
Description Seven (64%) of 11 MR images showed increased signal intensity in the basal ganglia. In 4 of 11 cases the T2- and proton densityweighted images showed a pronounced signal increase confined to the...
Article Title: The Heidenhain Variant of Creutzfeldt-Jakob Disease
Publication Title: Arch Neurol -
Description When similar analyses were performed in MS patients grouped according to duration of disease, 36 patients with early disease duration (3 years) still showed significantly lower brain NAA/Cr and MTr...
Article Title: Diffuse Axonal and Tissue Injury in Patients With Multiple Sclerosis With Low Cerebral Lesion Load and No Disability
Publication Title: Arch Neurol -
Description The autonomic disturbances were observed in all patients. They included sinus tachycardia (32 patients); arterial hypotension (32 patients) leading to collapses (11 patients); retention of urine...
Article Title: Diphtheritic Polyneuropathy
Publication Title: Arch Neurol -
Description defined consciousness as awareness of oneself (or one's own cognitive experience) and the environment. This apparently simple definition belies complex brain functions that involve numerous...
Article Title: Neurobiological Basis of Consciousness
Publication Title: Arch Neurol -
Description The length of the repeat tracts among individuals carrying at least 1 expanded SCA8 allele ranged between 90 and 320 combined CTA/CTG (Figure 2).
Article Title: Genetic and Clinical Analysis of Spinocerebellar Ataxia Type 8 Repeat Expansion in Italy
Publication Title: Arch Neurol -
Description Forty-nine (59%) of 83 patients with PPMS were women. The meanSD disease duration from the time of the first symptom was 14.28.8 years (median, 12.2 years; range, 1.9-36.4 years). The meanSD...
Article Title: Multiple Sclerosis That Is Progressive From the Time of Onset
Publication Title: Arch Neurol -
Description Figure 2 shows the densities of SPs at biopsy and autopsy for all cases. We found a marked, statistically significant increase of SP density in patients 3, 4, and 5, with counts at autopsy being...
Article Title: Progression of Clinical Deterioration and Pathological Changes in Patients With Alzheimer Disease Evaluated at Biopsy and Autopsy
Publication Title: Arch Neurol -
Description We found 5 different mutations of Park2 gene in 5 families with recessive inherited PD. The mutational spectrum includes 3 previously described deletions and 2 novel point mutations. A homozygous...
Article Title: Molecular Findings in Familial Parkinson Disease in Spain
Publication Title: Arch Neurol -
Description This family had 6 affected individuals in 1 generation (Figure 2). Their mean age of onset was 69.8 (SD, 11.1) years. All affected individuals presented initially with cognitive decline. In...
Article Title: Familial Dementia With Lewy Bodies
Publication Title: Arch Neurol -
Description In patients with ALS undergoing follow-up 1H-MRS measurements (n = 16), NAA/Cho ratio decreased by 9% (P = .003) and NAA/(P)Cr ratio by 2% (P = .49), whereas Cho/(P)Cr ratio increased by 7% (P =...
Article Title: Proton Magnetic Resonance Spectroscopy of the Motor Cortex in 70 Patients With Amyotrophic Lateral Sclerosis
Publication Title: Arch Neurol -
Description Patients who progressed from MCI to AD had significantly higher median CSF tau protein concentrations at baseline than subjects with stable MCI (P = .002) and controls (P.001) (Table 2). Patients...
Article Title: Cerebrospinal Fluid Tau and -Amyloid 42 Proteins Identify Alzheimer Disease in Subjects With Mild Cognitive Impairment
Publication Title: Arch Neurol -
Description Specific changes have been identified on magnetic resonance imaging (MRI) scans: cortical atrophy, ventricular enlargement, deep white-matter hyperintensities (DWMHs) in subcortical white matter,...
Article Title: Cognitive and Physiologic Correlates of Subclinical Structural Brain Disease in Elderly Healthy Control Subjects
Publication Title: Arch Neurol