Advanced Search
Displaying assets from 1 to 30 out of 2978
-
Description Factors increasing the risk of hypoglycaemia and its potential consequences in elderly people with diabetes. CVD, cardiovascular disease.
Article Title: Dipeptidyl peptidase‐4 inhibitors can minimize the hypoglycaemic burden and enhance safety in elderly people with diabetes
Publication Title: Diabetes, Obesity and Metabolism -
Description Demographically adjusted hazard ratio (95% confidence interval, CI) for developing diabetes associated with baseline metabolic syndrome and components. (A) Model adjusted for demographic factors....
Article Title: Metabolic syndrome components and their response to lifestyle and metformin interventions are associated with differences in diabetes risk in persons with impaired glucose tolerance
Publication Title: Diabetes, Obesity and Metabolism -
Description Islet morphology in treated and control rats. (A) Representative photomicrographs of islet cross sections, magnification ×10; α‐cells were labelled with an antiglucagon (red) antibody, β‐cells with...
Article Title: Taspoglutide, a novel human once‐weekly GLP‐1 analogue, protects pancreatic β‐cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo
Publication Title: Diabetes, Obesity and Metabolism -
- Identifier
- dom14215-fig-0002
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Glucagon‐like peptide‐1/glucose‐dependent insulinotropic polypeptide (GLP‐1/GIP) improves lipid metabolism with greater potency in diet‐induced obese male and female mice relative to treatment with...
Article Title: Plasma proteome profiles treatment efficacy of incretin dual agonism in diet‐induced obese female and male mice
Publication Title: Diabetes, Obesity and Metabolism -
Description Metabolic parameters in mice treated with DSP‐7238 for 11 weeks.
Article Title: Chronic administration of DSP‐7238, a novel, potent, specific and substrate‐selective DPP IV inhibitor, improves glycaemic control and β‐cell damage in diabetic mice
Publication Title: Diabetes, Obesity and Metabolism -
Description Oral glucose tolerance test (OGTT). Glucose (A) and insulin (B) levels during OGTT for anakinra (dark grey) and placebo (light grey) treatment. The area under the curve (AUC) for glucose during the...
Article Title: The interleukin‐1 receptor antagonist anakinra improves first‐phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance
Publication Title: Diabetes, Obesity and Metabolism -
Description Participant flow during the LEAD‐3 trial. ITT, intention‐to‐treat.
Article Title: Liraglutide, a once‐daily human glucagon‐like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes
Publication Title: Diabetes, Obesity and Metabolism -
Description Flow of participants in the ORBIT study. Participants without a successful clinical visit within a 1‐month follow‐up window at month 3 or month 6 were defined as lost to follow‐up. Participants not...
Article Title: Observational Registry of Basal Insulin Treatment (ORBIT) in patients with type 2 diabetes uncontrolled with oral antihyperglycaemic drugs: Real‐life use of basal insulin in China
Publication Title: Diabetes, Obesity and Metabolism -
Description Outcomes by MetS at baseline. Cumulative hazards for the primary outcome (a composite of myocardial infarction, acute coronary syndrome, stroke, heart failure, or death from cardiovascular causes)...
Article Title: Influence of metabolic syndrome and race on the relationship between intensive blood pressure control and cardiovascular outcomes in the SPRINT cohort
Publication Title: Diabetes, Obesity and Metabolism -
Description Comparison of epicardial fat volume and hepatic triglyceride content change between patients with or without significant weight loss (<5% or ≥5%) in exenatide subgroup. **p < 0.01, ***p < 0.001....
Article Title: Exenatide decreases liver fat content and epicardial adipose tissue in patients with obesity and type 2 diabetes: a prospective randomized clinical trial using magnetic resonance imaging and spectroscopy
Publication Title: Diabetes, Obesity and Metabolism -
-
Description Serum lipid profile (A–C) and serum glucose (D–F) among the experimental treatment groups (n = 10–14 per experimental group; see legend for Figure ) at the end of the study (at 15 weeks). IAP,...
Article Title: Prevention of antibiotic‐associated metabolic syndrome in mice by intestinal alkaline phosphatase
Publication Title: Diabetes, Obesity and Metabolism -
Description Relative risk (RR) with 95% confidence interval (CI) associated with the use of sitagliptin monotherapy compared with metformin monotherapy for meeting the specific endpoints (i.e. all‐cause...
Article Title: All‐cause mortality and cardiovascular effects associated with the DPP‐IV inhibitor sitagliptin compared with metformin, a retrospective cohort study on the Danish population
Publication Title: Diabetes, Obesity and Metabolism -
Description (A) Chemical structure of AS1535907; (B) GPR119 agonist activity (EC50 = 1.5 µM) of AS1535907 in HEK293 cells (n = 3); (C) insulin secretion in mouse β‐cell line NIT‐1 (n = 6); (D) human insulin...
Article Title: The role of small molecule GPR119 agonist, AS1535907, in glucose‐stimulated insulin secretion and pancreatic β‐cell function
Publication Title: Diabetes, Obesity and Metabolism -
Description Odds ratio and 95% confidence intervals for the risk of diabetes mellitus by quartiles of ferritin and sTfR derived from conditional logistic regression models
Article Title: Biomarkers of body iron stores and risk of developing type 2 diabetes
Publication Title: Diabetes, Obesity and Metabolism -
Description Mean (± standard error) change of plasma glucose and insulin concentrations from Day 1 pre‐dosing values during a 50 g oral glucose tolerance test performed at baseline and Day 12. Data includes...
Article Title: Remogliflozin etabonate, a selective inhibitor of the sodium‐dependent transporter 2 reduces serum glucose in type 2 diabetes mellitus patients
Publication Title: Diabetes, Obesity and Metabolism -
Description Effect of treatment of ZDF rats with AVE7688 on body weight, blood pressure, blood glucose, serum insulin, cholesterol, triglycerides, free fatty acids, TBARS and ACE, liver conjugated diene,...
Article Title: Treatment of Zucker diabetic fatty rats with AVE7688 improves vascular and neural dysfunction
Publication Title: Diabetes, Obesity and Metabolism -
Description Evaluation of risk of bias in the studies included in the meta‐analysis.
Article Title: Effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 (PCSK9) concentrations: a systematic review and meta‐analysis of clinical trials
Publication Title: Diabetes, Obesity and Metabolism -
Description Relative GPR120 fluorescence intensity of BRIN‐BD11 cells after exposure to GPR120 agonists at 10−4 mol/l at 11.1 mmol/l glucose for 20 min. GPR120 in the presence of (A) 11.1 mmol/l glucose, (B)...
Article Title: Evaluation of the insulin‐releasing and glucose‐lowering effects of GPR120 activation in pancreatic β‐cells
Publication Title: Diabetes, Obesity and Metabolism -
Description Predicted versus observed rates across deciles of A, 3‐year, B, 5‐year, C, 10‐year, D, 15‐year all‐cause mortality and E, 3‐year, F, 5‐year, G, 10‐year and H, 15‐year expanded...
Article Title: Building clinical risk score systems for predicting the all‐cause and expanded cardiovascular‐specific mortality of patients with type 2 diabetes
Publication Title: Diabetes, Obesity and Metabolism -
Description Response of fasting glucose (A), fasting insulin (B), HOMA2 insulin resistance (C) and HOMA2 insulin sensitivity (D) to a single session of resistance exercise. 0 h is immediately before resistance...
Article Title: Insulin sensitivity not modulated 24 to 78 h after acute resistance exercise in type 2 diabetes patients
Publication Title: Diabetes, Obesity and Metabolism -
Description Long‐term changes in haemoglobin A1c (HbA1c) levels and body weight. T0 indicates the baseline time point; T1, the time point of glycaemic nadir or month 12 for studies without an obvious HbA1c...
Article Title: Durability of glycaemic control in type 2 diabetes: A systematic review and meta‐analysis for its association with body weight changes
Publication Title: Diabetes, Obesity and Metabolism -
Description Effect of MK‐0916 on adrenal androgens at week 12 (treatment) and week 15 (post‐treatment).
Article Title: Effects of an 11β‐hydroxysteroid dehydrogenase type 1 inhibitor, MK‐0916, in patients with type 2 diabetes mellitus and metabolic syndrome
Publication Title: Diabetes, Obesity and Metabolism -
Description Kaplan–Meier estimated cumulative incidence of any fracture according to treatment assignment (sitagliptin vs placebo).
Article Title: Sitagliptin and risk of fractures in type 2 diabetes: Results from the TECOS trial
Publication Title: Diabetes, Obesity and Metabolism -
Description An aortic ring section showing the lines encompassing areas A and L. The area of atheroma is expressed as: AA = log10 .
Article Title: The effects of magnesium sulphate and EDTA in the hypercholesterolaemic rabbit
Publication Title: Diabetes, Obesity and Metabolism -
Description GLP‐1R activation by liraglutide impaired the growth of human pancreatic cancer cells. MIA PaCa‐2 (A) and PANC‐1 cells (B) were assessed by colony formation assay. Data are shown as means ± SD. n =...
Article Title: Activation of glucagon‐like peptide‐1 receptor inhibits tumourigenicity and metastasis of human pancreatic cancer cells via PI3K/Akt pathway
Publication Title: Diabetes, Obesity and Metabolism -
Description Glucose responsiveness is suppressed by immunosuppressant pretreatment. RIN‐5F cells were treated with 50 nm tacrolimus, 7 mm CsA, 100 nm rapamycin (rap) or nothing for 60 min in complete RPMI‐1640...
Article Title: Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP‐sensitive potassium channel
Publication Title: Diabetes, Obesity and Metabolism -
Description Preclinical and clinical SGLT1, SGLT2 and dual SGLT1/2 inhibitors
Article Title: What does sodium‐glucose co‐transporter 1 inhibition add: Prospects for dual inhibition
Publication Title: Diabetes, Obesity and Metabolism -
Description TABLE
Article Title: Relationship between peripheral neuropathy, diastolic function and adverse cardiovascular outcome in individuals with type 1 diabetes mellitus without known cardiovascular disease: Results from the Thousand & 1 Study
Publication Title: Diabetes, Obesity and Metabolism -
Description Effects of hyperglycaemia on complications of COVID‐19: A meta‐analysis of observational studiesLee et al. - Diabetes, Obesity and MetabolismDiabetes Obes Metab vol. 23, January 2021
Article Title: Effects of hyperglycaemia on complications of COVID‐19: A meta‐analysis of observational studies
Publication Title: Diabetes, Obesity and Metabolism