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Description Several miRNAs as tumor suppressor in leukemia
Article Title: MicroRNA in leukemia: Tumor suppressors and oncogenes with prognostic potential
Publication Title: Journal of Cellular Physiology -
Description miR‐488 inhibits LPS‐mediated AKT/NF‐κB pathway activity. (a,b) BEND cells were transfected with miR‐488 mimics or mimics NC for 24 hr and then stimulated with LPS (2 μg/ml) for 12 hr. The...
Article Title: miR‐488 mediates negative regulation of the AKT/NF‐κB pathway by targeting Rac1 in LPS‐induced inflammation
Publication Title: Journal of Cellular Physiology -
Description FHL1 overexpression does not influence muscle cell differentiation. (a, b) Cells were transfected with FHL1 plasmids or empty vector controls, and then cultured in GM or induced to differentiate...
Article Title: FHL1 regulates myoblast differentiation and autophagy through its interaction with LC3
Publication Title: Journal of Cellular Physiology -
Description A simplified schematic diagram indicates that the OMVs from AD patients stimulate glial cell activity and influence the activity of GSK3β and the phosphorylation of tau. AD, Alzheimer's disease;...
Article Title: Outer membrane vesicles enhance tau phosphorylation and contribute to cognitive impairment
Publication Title: Journal of Cellular Physiology -
Description Wild‐type RhoGDIβ, but not the mutant D19A‐RhoGDIβ, confers UVC‐induced spindle misorientation in RhoGDIβ‐knockdown cells. (a) UVC‐irradiated and nonirradiated metaphase‐synchronized cells (clones...
Article Title: RhoGDIβ affects HeLa cell spindle orientation following UVC irradiation
Publication Title: Journal of Cellular Physiology -
Description Expression of MCL1 in TNBC tissues and cell lines. (a) MCL1 expression was determined in 21 TNBC specimens (T) compared to normal tissues by real‐time RT‐PCR. (b) MCL1 expression was also...
Article Title: Loss of MCL1 function sensitizes the MDA‐MB‐231 breast cancer cells to rh‐TRAIL by increasing DR4 levels
Publication Title: Journal of Cellular Physiology -
Description The expression of P‐nucleolin/nucleolin in apoptosis of H9C2 cells induced by H2O2. (a) The effect of H2O2 (0.5 mM, 0–24 hr) on cell viability. (b) The effect of H2O2 (0.5 mM, 0–24 hr) on caspase‐3...
Article Title: Phosphorylation of nucleolin is indispensable to upregulate miR‐21 and inhibit apoptosis in cardiomyocytes
Publication Title: Journal of Cellular Physiology -
Description Cyclooxygenase‐2 (COX‐2) promoter. AP‐2: activator protein‐2; ARE: AU‐rich elements; CRE: cyclic AMP response element; CREB: CRE protein binding; HuR: Hu Antigen‐R; IL: interleukin; mRNA: messenger...
Article Title: Cyclooxygenase‐2 in cancer: A review
Publication Title: Journal of Cellular Physiology -
Description (a) Heat map of differential genes between tumor metastatic group and tumor primary group. (b) The volcano figure of differential genes. The blue represents the relatively downregulated genes and...
Article Title: Identification of the potential prognostic genes of human melanoma
Publication Title: Journal of Cellular Physiology -
Description γ‐Glutamyltranspeptidase (GGT) activity in bovine zygotes treated with exogenous glutathione (GSH). The enzyme activity of GGT in zygotes at 8, 18, 24, and 32‐hr postinsemination (hpi), cultured in...
Article Title: Exogenous glutathione improves intracellular glutathione synthesis via the γ‐glutamyl cycle in bovine zygotes and cleavage embryos
Publication Title: Journal of Cellular Physiology -
Description Ingenuity pathway analysis of the common significant differentially expressed genes to identify the canonical pathways involving ASC osteogenic differentiation. ASC: adipose stem cell [Color figure...
Article Title: Identification of key genes and pathways associated with osteogenic differentiation of adipose stem cells
Publication Title: Journal of Cellular Physiology -
Description List of genes with their forward and reverse primer sequences used for the gene expression analysis by real‐time quantitative polymerase chain reaction
Article Title: Arsenic induces fibrogenic changes in human kidney epithelial cells potentially through epigenetic alterations in DNA methylation
Publication Title: Journal of Cellular Physiology -
Description The involvement of SMADs and p38 signaling in Mg‐induced osteogenesis differentiation. (a,b) BMSCs were cotransfected with LOC103691336 shRNA and miR‐138 inhibitor in the presence or absence of...
Article Title: LOC103691336/miR‐138‐5p/BMPR2 axis modulates Mg‐mediated osteogenic differentiation in rat femoral fracture model and rat primary bone marrow stromal cells
Publication Title: Journal of Cellular Physiology -
Description Dacarbazine enhanced the inhibitory effect of statins on cell invasion, migration, and adhesion. (a) B16BL6, (b) A375, or (c) RPMI7951 cells were pretreated with 0.1 μM simvastatin, 0.05 μM...
Article Title: Combination therapy with dacarbazine and statins improved the survival rate in mice with metastatic melanoma
Publication Title: Journal of Cellular Physiology -
Description Mimicking the lens electrical signal promoted differentiation in human lens epithelial cells (HLECs). (a–d). HLECs were harvested at different culture times for western blotting. The expression of...
Article Title: Endogenous bioelectric currents promote differentiation of the mammalian lens
Publication Title: Journal of Cellular Physiology -
Description Relationship between GPX4 and chemoresistance of cancer and the potential function of GPX4. (a–d) Expression of GPX4 was positively correlated to IC50 of L–685458 (a), Lapatinib (b), Palbociclib...
Article Title: Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin
Publication Title: Journal of Cellular Physiology -
Description Schematic diagram showing the classical pathway of Nrf2 regulation: In normal unstressed cells, Nrf2 is sequestered in the cytosol and degraded by Cul3/Rbx1. Keap1 acts as an adaptor in this...
Article Title: Nrf2–ARE signaling in cellular protection: Mechanism of action and the regulatory mechanisms
Publication Title: Journal of Cellular Physiology -
Description primers used for RT‐PCR
Article Title: Role of IL‐6‐mediated expression of NS5ATP9 in autophagy of liver cancer cells
Publication Title: Journal of Cellular Physiology -
Description The revealed aberrantly methylated genes that were significantly associated with OS after univariate Cox regression analysis
Article Title: Prognostic value of aberrantly expressed methylation gene profiles in lung squamous cell carcinoma: A study based on The Cancer Genome Atlas
Publication Title: Journal of Cellular Physiology -
Description Schematic diagram of the mechanism involved in the protective role of curcumin against high glucose‐induced damage in RPE cells. Nrf2: nuclear factor erythroid 2‐related factor 2; ROS: reactive...
Article Title: Curcumin prevents high glucose damage in retinal pigment epithelial cells through ERK1/2‐mediated activation of the Nrf2/HO‐1 pathway
Publication Title: Journal of Cellular Physiology -
Description Conceptual diagram illustrating the cleavage of the key EMT marker E‐cadherin by calpain and the promoting role of calpains in both canonical Wnt/β‐catenin and noncanonical Wnt5A signaling pathways...
Article Title: Evidence for calpains in cancer metastasis
Publication Title: Journal of Cellular Physiology -
Description Catecholamine reduces the levels of Bag5 through the MAPK–ERK pathway. (a) ELISA for ERK activity in catecholamine‐treated endothelial cells. t‐Butylhydroquinone was used to activate ERK activity....
Article Title: Bcl‐2‐associated athanogene 5 overexpression attenuates catecholamine‐induced vascular endothelial cell apoptosis
Publication Title: Journal of Cellular Physiology -
Description Caspase‐12 knockout attenuated the stretch‐induced apoptosis of myoblasts. (a) Myoblasts were transfected with lentivirus vector containing caspase‐12 shRNA #1–#4. Forty‐eight hours after...
Article Title: Cleavage of caspase‐12 at Asp94, mediated by endoplasmic reticulum stress (ERS), contributes to stretch‐induced apoptosis of myoblasts
Publication Title: Journal of Cellular Physiology -
Description PAM‐1/H3A fails to form native complexes with V‐ATPase. (a) Lysates prepared from AtT‐20 cells expressing PAM‐1 or PAM‐1/H3A were subjected to immunoprecipitation as described in Figure a. PAM...
Article Title: A pH‐sensitive luminal His‐cluster promotes interaction of PAM with V‐ATPase along the secretory and endocytic pathways of peptidergic cells
Publication Title: Journal of Cellular Physiology -
Description CUL4A and CUL4B were direct targets of miR‐194‐5p. (a) Schematic representation of the 3′‐UTRs of CUL4A and CUL4B, containing a putative miR‐194‐5p binding site. The binding positions of miR‐194‐5p...
Article Title: Inflammation‐dependent downregulation of miR‐194‐5p contributes to human intervertebral disc degeneration by targeting CUL4A and CUL4B
Publication Title: Journal of Cellular Physiology -
Description Clinical Pharmacology of asparaginases with frequently administered doses
Article Title: Bacterial l‐asparaginases for cancer therapy: Current knowledge and future perspectives
Publication Title: Journal of Cellular Physiology -
Description Quantitative MDR1 transcript after treatment of MDA‐MB‐231RDB cells with IC10 of liposomal structures for 24 (a) and 48 hr (b). Results have been represented as mean ± SEM of three independent...
Article Title: Intelligent TAT‐coupled anti‐HER2 immunoliposomes knock downed MDR1 to produce chemosensitize phenotype of multidrug resistant carcinoma
Publication Title: Journal of Cellular Physiology -
- Identifier
- jcp24396-fig-0005
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Effect of gain and loss of runx activity on aggrecan mRNA and promoter activity. A: Gain of function: Top part: Effect of over expression of Runx1, 2, 3 or a Dominant Negative Runx (DN) expression...
Article Title: Functional role of Runx3 in the regulation of aggrecan expression during cartilage development
Publication Title: Journal of Cellular Physiology -
Description The sequences of the primers for qRT‐PCR
Article Title: Slug mediates myofibroblastic differentiation to promote fibrogenesis in buccal mucosa
Publication Title: Journal of Cellular Physiology -
Description The morphology, cytoskeleton protein expression levels, and Rho‐GTPase activity of the Ndrg2+/+, Ndrg2−/−, and Ndrg2−/− + LV‐Ndrg2 astrocytes, (a) Representative immunofluorescence images showing...
Article Title: N‐myc downstream‐regulated gene 2 controls astrocyte morphology via Rho‐GTPase signaling
Publication Title: Journal of Cellular Physiology