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Description Receiver operator curve (ROC) for Innovance D‐dimer assay. Dd, D‐dimer; DVT, deep vein thrombosis; FEU, fibrinogen equivalent units; Pos, Positive; Neg, negative; Dd Pos, level at or above...
Article Title: D‐dimer testing in pregnant patients: towards determining the next ‘level’ in the diagnosis of deep vein thrombosis
Publication Title: Journal of Thrombosis and Haemostasis -
Description Demographic and clinical characteristics
Article Title: The CD14++CD16+ monocyte subset and monocyte‐platelet interactions in patients with ST‐elevation myocardial infarction
Publication Title: Journal of Thrombosis and Haemostasis -
Description Isothermal titration calorimetry data showing the interaction between human serum albumin (HSA) and Zn2+ in the presence of 0 mol eq. (○), 1 mol eq. (●), 2 mol eq. (), 3 mol eq. (▼) and 5 mol eq....
Article Title: Plasma free fatty acid levels influence Zn2+‐dependent histidine‐rich glycoprotein–heparin interactions via an allosteric switch on serum albumin
Publication Title: Journal of Thrombosis and Haemostasis -
Description Logistic regression results of positive Single‐nucleotide polymorphisms (SNPs) under an additive genetic model
Article Title: Genome‐wide association study validation identifies novel loci for atherosclerotic cardiovascular disease
Publication Title: Journal of Thrombosis and Haemostasis -
Description Nerve growth factor (NGF) but not epidermal growth factor (EGF), stimulates Plasminogen (Plg) promoter activity in PC‐12 cells. PC‐12 cells (2 × 105) were grown in 12‐well plates to 70–80%...
Article Title: Plasminogen gene expression is regulated by nerve growth factor
Publication Title: Journal of Thrombosis and Haemostasis -
Description The mechanisms of thrombopoietin receptor activation. Thrombopoietin (TPO) and romiplostim bind to the extracellular domain of TPO receptor, Mpl. In contrast, eltrombopag binds to the transmembrane...
Article Title: Development of thrombopoietin receptor agonists for clinical use
Publication Title: Journal of Thrombosis and Haemostasis -
Description Phosphatidylserine (PS) exposure precedes loss of viability on fresh APL cells. (A) Fresh APL cells from a bone marrow aspirate were incubated for 24–48 h in culture medium. Most cells had low...
Article Title: Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia
Publication Title: Journal of Thrombosis and Haemostasis -
Description Study flow
Article Title: Trial of Rivaroxaban in AntiPhospholipid Syndrome (TRAPS): Two‐year outcomes after the study closure
Publication Title: Journal of Thrombosis and Haemostasis -
Description TABLE
Article Title: Placenta‐mediated complications: Nucleosomes and free DNA concentrations differ depending on subtypes
Publication Title: Journal of Thrombosis and Haemostasis -
Description PAI‐2 deficiency enhances thrombus resolution and decreases PAI‐1 levels. (A) Thrombus weight normalized to mouse body weight over time in PAI‐2−/− mice compared to WT (day 12, P < 0.005, n =...
Article Title: Enhanced venous thrombus resolution in plasminogen activator inhibitor type‐2 deficient mice
Publication Title: Journal of Thrombosis and Haemostasis -
Description Effect of fondaparinux (FPX) on plasma markers of organ functions. A, lactate; B, glucose; C, blood urea nitrogen (BUN); D, creatinine; and E, alanine aminotransferase (ALT). Data are presented as...
Article Title: Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of Escherichia coli sepsis
Publication Title: Journal of Thrombosis and Haemostasis -
Description von Willebrand factor (VWF) parameters in thrombotic thrombocytopenic purpura (TTP) patients during (a) an acute episode and (b) remission as compared with controls
Article Title: von Willebrand factor propeptide to antigen ratio in acquired thrombotic thrombocytopenic purpura
Publication Title: Journal of Thrombosis and Haemostasis -
Description Patients with congenital hemophilia and healthy controls
Article Title: Inhibition of tissue factor pathway inhibitor by the aptamer BAX499 improves clotting of hemophilic blood and plasma
Publication Title: Journal of Thrombosis and Haemostasis -
Description Postaspirin platelet aggregation (%) in response to 5 μm ADP, 1.5 mm arachidonic acid and 1 μg mL−1 collagen in tertiles of % reticulated platelets.
Article Title: Reticulated platelets and uninhibited COX‐1 and COX‐2 decrease the antiplatelet effects of aspirin
Publication Title: Journal of Thrombosis and Haemostasis -
Description Subclass distribution of anti‐ADAMTS13 IgG antibodies in patients with acquired thrombotic thrombocytopenic purpura. Fifty‐eight patients with acute acquired TTP were analyzed for different IgG...
Article Title: IgG subclass distribution of anti‐ADAMTS13 antibodies in patients with acquired thrombotic thrombocytopenic purpura
Publication Title: Journal of Thrombosis and Haemostasis -
Description Real‐time polymerase chain reaction (PCR) studies of tissue‐specific expression of PFX1, PFX2 and pseutarin C catalytic subunit (PCCS). Amplification curves (delta Rn) of PFX1, PFX2 and PCCS in...
Article Title: Molecular evolution caught in action: gene duplication and evolution of molecular isoforms of prothrombin activators in Pseudonaja textilis (brown snake)
Publication Title: Journal of Thrombosis and Haemostasis -
Description Stacking histogram showing the clottable protein mean laboratory potency estimates (as a percentage of proposed mean potency) for the 2nd International Standard (IS) candidate B relative to the 1st...
Article Title: International collaborative study to establish the World Health Organization 2nd International Standard for Fibrinogen Concentrate (09/242): communication from the SSC of the ISTH
Publication Title: Journal of Thrombosis and Haemostasis -
Description Role of P2Y1 in the platelet shape change induced by collagen. Washed human platelets, pretreated with MRS2179, AR‐C69931MX or aspirin as in Fig. 1 (A), were stimulated with collagen (100 µg mL−1)...
Article Title: The P2Y1 receptor plays an essential role in the platelet shape change induced by collagen when TxA2 formation is prevented
Publication Title: Journal of Thrombosis and Haemostasis -
Description Lysis by red blood cell‐plasminogen activator (RBC‐PA) differs from lysis by free PA. Lysis by free PA (0.00820 μM, final conc) + 1% human RBCs (hRBCs) (A) or 1% RBC‐PA (B) as a function of time...
Article Title: The spatial dynamics of fibrin clot dissolution catalyzed by erythrocyte‐bound vs. free fibrinolytics
Publication Title: Journal of Thrombosis and Haemostasis -
Description Sustained αIIbβ3 activation on platelets stimulated with U46619. (A) Experiments were performed as in Fig. 2 using 5 μm U46619 instead of thrombin. One micromolar AR‐C69931MX (AR‐C) or 1 mm A3P5P...
Article Title: Critical role of ADP interaction with P2Y12 receptor in the maintenance of αIIbβ3 activation: association with Rap1B activation
Publication Title: Journal of Thrombosis and Haemostasis -
Description Injection of 9O12.2 Fab inhibits collagen‐induced thrombus formation ex vivo. Whole blood was collected into hirudin before and after injection of 9O12.2 Fab (4 mg kg−1) or vehicle into cynomolgus...
Article Title: Ex vivo inhibition of thrombus formation by an anti‐glycoprotein VI Fab fragment in non‐human primates without modification of glycoprotein VI expression
Publication Title: Journal of Thrombosis and Haemostasis -
Description The factor XIIIa (FXIIIa) and TG2‐reactive cross‐linking sites of fibrin are located in the C‐terminal domains of the γ and α chains of the protein. Approximate locations for the FXIIIa‐reactive...
Article Title: Factor XIII and the clotting of fibrinogen: from basic research to medicine
Publication Title: Journal of Thrombosis and Haemostasis -
Description Stress‐induced glomerular fibrin deposition in obese and lean mice. Renal tissues were removed from 6‐week‐old obese and lean mice after 2 h‐restraint stress (n = 8), and then, analyzed by...
Article Title: Obesity enhances the induction of plasminogen activator inhibitor‐1 by restraint stress: a possible mechanism of stress‐induced renal fibrin deposition in obese mice
Publication Title: Journal of Thrombosis and Haemostasis -
Description ROTEM EXTEM variables before and after fresh frozen plasma (FFP) transfusion (12 mL kg−1). Dotted lines indicate reference ranges. CFT, clot formation time; CT, clotting time; MCF, maximum clot...
Article Title: Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy
Publication Title: Journal of Thrombosis and Haemostasis -
Description Associations between negative affect domains and prothrombotic measures within and between the two patient groups
Article Title: Relation of psychological distress to the international normalized ratio in patients with venous thromboembolism with and without oral anticoagulant therapy
Publication Title: Journal of Thrombosis and Haemostasis -
Description Effect of protein S on tissue factor (TF) pathway inhibitor (TFPI) inhibition of FXa and FVIIa–TF. Reactions in Tris‐buffered saline (50 mm Tris, 150 mm NaCl, pH 7.4) contained 5 mm CaCl2 and 25 μm...
Article Title: Protein S enhances the tissue factor pathway inhibitor inhibition of factor Xa but not its inhibition of factor VIIa–tissue factor
Publication Title: Journal of Thrombosis and Haemostasis -
Description Effect of FXIII catalytic A2 subunit deficiency on carbon tetrachloride (CCl4)‐induced hepatic fibrin(ogen) deposition. Wild‐type (WT) and FXIII−/− mice were treated with CCl4 or vehicle for 6...
Article Title: Chronic liver injury drives non‐traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase
Publication Title: Journal of Thrombosis and Haemostasis -
Description Naïve baboon serum activates PAECs to induce TF activity that is complement dependent. (A) WT (whites bars) or CD46 (gray bars) PAECs were incubated with medium (control) or (at a series of...
Article Title: Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by anti‐nonGal IgG binding to porcine aortic endothelial cells
Publication Title: Journal of Thrombosis and Haemostasis -
Description Individual study relative risks and pooled estimate for any deep vein thrombosis.
Article Title: Anticoagulant prophylaxis to prevent asymptomatic deep vein thrombosis in hospitalized medical patients: a systematic review and meta‐analysis
Publication Title: Journal of Thrombosis and Haemostasis -
Description Half‐lives of fusion transcripts
Article Title: Identification of tristetraprolin as a factor that modulates the stability of the TAFI transcript through binding to the 3′‐untranslated region
Publication Title: Journal of Thrombosis and Haemostasis