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Displaying assets 1 - 30 of 4980 in total. Search results limited to 100 out of 166 pages. Please refine your search query.
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Description Intralaboratory correlation between the activated partial thromboplastin time (APTT) and FXa inhibition assays. (A–D) Relationship between the APTT and FXa inhibition assays (anti‐FXa) in each...
Article Title: Interlaboratory agreement in the monitoring of unfractionated heparin using the anti‐factor Xa‐correlated activated partial thromboplastin time
Publication Title: Journal of Thrombosis and Haemostasis -
Description Supplementation of FXIII‐deficient plasma by the missing factor restores clot stiffness (left) and resistance against lysis by TPA (right). Additions of purified human plasma FXIII (left panel;...
Article Title: Factor XIII and the clotting of fibrinogen: from basic research to medicine
Publication Title: Journal of Thrombosis and Haemostasis -
Description FXa and thrombin provide a partial barrier protective effect against vascular endothelial growth factor (VEGF)‐induced hyperpermeability independently of endothelial cell protein C receptor (EPCR)....
Article Title: Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo
Publication Title: Journal of Thrombosis and Haemostasis -
Description Effect of the combination idraparinux + unfractionated heparin (UFH) on activated partial thromboplastin time (APTT). Mean of three experiments.
Article Title: In vitro interaction of the pentasaccharide idraparinux (SanOrg 34006) with unfractionated heparin
Publication Title: Journal of Thrombosis and Haemostasis -
Description Postaspirin platelet aggregation (%) in response to 5 μm ADP, 1.5 mm arachidonic acid and 1 μg mL−1 collagen in tertiles of % reticulated platelets.
Article Title: Reticulated platelets and uninhibited COX‐1 and COX‐2 decrease the antiplatelet effects of aspirin
Publication Title: Journal of Thrombosis and Haemostasis -
Description Recombinant shortA1 and longA1 proteins are primarily monomeric, and shortA1, but not longA1, binds GPIbα. (A) Illustrations of shortA1 and longA1 proteins. Both proteins contain a C‐terminal...
Article Title: A discontinuous autoinhibitory module masks the A1 domain of von Willebrand factor
Publication Title: Journal of Thrombosis and Haemostasis -
Description Work flow for fluorescent cell barcoding (FCB), deconvolution, and data presentation. Various concentrations of Pacific Blue and Alexa Fluor 488 dyes were added to the wells of a 96‐well plate. The...
Article Title: Multiplexed phosphospecific flow cytometry enables large‐scale signaling profiling and drug screening in blood platelets
Publication Title: Journal of Thrombosis and Haemostasis -
Description Corn trypsin inhibitor (CTI) substitutions affect inhibition of activated factor XII (FXIIa) to different degrees. (A) The CTI amino acid sequence for residues 20–44 with the respective contact...
Article Title: Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
Publication Title: Journal of Thrombosis and Haemostasis -
Description 3D1 inhibited glycoprotein (GP)Ibα shedding in human platelets, and had no detectable effect on platelet aggregation and activation. (A) Overlaid flow cytometry histograms showing the inhibition of...
Article Title: Dimerization of glycoprotein Ibα is not sufficient to induce platelet clearance
Publication Title: Journal of Thrombosis and Haemostasis -
Description Mean (± standard deviation) inhibition of activated factor X (FXa) activity in healthy subjects repeating the study protocol 10–14 months following the original dose (3 mg idrabiotaparinux followed...
Article Title: Reversibility of the anti‐FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion
Publication Title: Journal of Thrombosis and Haemostasis -
Description Scanning transmission electron microscopy images of purified fibrinogen without (A) and with (B) the addition of γ365–380 peptide (molar ratio 10:1). The peptide‐containing sample shows a tendency...
Article Title: Changes in fibrinogen and fibrin induced by a peptide analog of fibrinogen γ365–380
Publication Title: Journal of Thrombosis and Haemostasis -
Description Effect of A2b adenosine receptor (A2bAR) activation on platelet aggregation. (A) Electron microscopic examination of platelets at 1 day after femoral artery injury (FAI), a time point at which...
Article Title: A new role for the A2b adenosine receptor in regulating platelet function
Publication Title: Journal of Thrombosis and Haemostasis -
Description Correlations between myeloid endothelial progenitor cells (mEPC) number and markers of vascular injury: pulse wave velocity (PWV) (A) and endothelial microparticles (EMP) plasma levels (B). mEPC...
Article Title: Levels of circulating endothelial progenitor cells are related to uremic toxins and vascular injury in hemodialysis patients
Publication Title: Journal of Thrombosis and Haemostasis -
Description Oscillatory shear stress (OSS) induces sustained BMPRIB‐αvβ3 integrin association, which is mediated by the intracytoplasmic kinase domain of BMPRII in endothelial cells (ECs). ECs were exposed to...
Article Title: BMP receptor‐integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow
Publication Title: Journal of Thrombosis and Haemostasis -
Description Correlations between coagulation parameters. Correlations between free tissue factor pathway inhibitor (TFPI) and full‐length TFPI levels (A), total TFPI levels (determined with the commercial...
Article Title: Thrombin generation‐based assays to measure the activity of the TFPI–protein S pathway in plasma from normal and protein S‐deficient individuals
Publication Title: Journal of Thrombosis and Haemostasis -
Description Ability of rFIX(a) to support plasma thrombin generation (TG) in FIX‐deficient plasma. Representative TG curves showing dose dependence in the presence of (A) 0%, 1%, 5%, 10%, 25%, and 100% rFIX‐WT...
Article Title: Selective disruption of heparin and antithrombin‐mediated regulation of human factor IX
Publication Title: Journal of Thrombosis and Haemostasis -
Description Tissue factor (A), IL8 (B), and monocyte chemotactic protein‐1 (C) mRNA levels in whole blood pre‐incubated with 5 ng mL−1 recombinant human IL10 (dark gray) before stimulation with 20 μm thrombin...
Article Title: Tissue factor and IL8 production by P‐selectin‐dependent platelet–monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10
Publication Title: Journal of Thrombosis and Haemostasis -
Description Identification of the glycoprotein (GP)Ibβ domains binding to platelet 14‐3‐3 isoforms. CHO cells transfected with GPIb–IX containing the normal sequence (Ib–IX) or with the GPIbβ intracytoplasmic...
Article Title: Identification of five novel 14‐3‐3 isoforms interacting with the GPIb–IX complex in platelets
Publication Title: Journal of Thrombosis and Haemostasis -
Description Promotion of intermolecular pro‐PHBP complex formation by spermidine. (A) Size‐exclusion chromatography. 125I‐Pro‐PHBP (10 μg; 100 000 cpm) was subjected to analytical size‐exclusion HPLC in the...
Article Title: Polyamine‐promoted autoactivation of plasma hyaluronan‐binding protein
Publication Title: Journal of Thrombosis and Haemostasis -
Description Nuclear localization of p45 NF‐E2. p45 NF‐E2 fused to eGFP was transfected into COS‐7 cells and analyzed by confocal laser scanning microscopy (CLSM) 48 h later (top panel). V5‐tagged p45 NF‐E2 was...
Article Title: A monopartite sequence is essential for p45 NF‐E2 nuclear translocation, transcriptional activity and platelet production
Publication Title: Journal of Thrombosis and Haemostasis -
Description Cumulative incidence of thromboembolic events in patients with antiphospholipid syndrome (APS) and triple laboratory positivity according to treatment with oral anticoagulants during follow‐up (OA,...
Article Title: Clinical course of high‐risk patients diagnosed with antiphospholipid syndrome
Publication Title: Journal of Thrombosis and Haemostasis -
Description Individual study relative risks and pooled estimate for any deep vein thrombosis.
Article Title: Anticoagulant prophylaxis to prevent asymptomatic deep vein thrombosis in hospitalized medical patients: a systematic review and meta‐analysis
Publication Title: Journal of Thrombosis and Haemostasis -
Description Histological and immunostaining of peritoneum. Slices of peritoneum of cecal ligation and puncture‐antithrombin (CLP‐AT; A and B), CLP‐saline (C and D) and sham mice (E and F) were stained with...
Article Title: Anticoagulant and anti‐inflammatory effects after peritoneal lavage with antithrombin in experimental polymicrobial peritonitis
Publication Title: Journal of Thrombosis and Haemostasis -
Description Inhibitory effect of activated FV [FV(a)] subunits on thrombin‐catalyzed FV activation. FV activity was measured using the one‐stage method after adding thrombin (2 nmol L−1) to FV (20 nmol L−1)....
Article Title: Factor V C2 domain contains a major thrombin‐binding site responsible for thrombin‐catalyzed factor V activation
Publication Title: Journal of Thrombosis and Haemostasis -
Description Enhanced tissue factor (TF) expression levels by heparanase transgenic (Tg) mice. (A) Immunoblotting. Lung, kidney, liver and heart tissues were harvested from control (C, left) and heparanase Tg...
Article Title: Heparanase induces tissue factor expression in vascular endothelial and cancer cells
Publication Title: Journal of Thrombosis and Haemostasis -
Description Inhibition of elastase‐induced fibrin clot lysis by fibrin(ogen)‐bound A1AT present in purified fibrinogen. Fibrin clots of 0.4 mg mL−1 were prepared by mixing purified fibrinogen (closed circles)...
Article Title: Identification and characterization of α1‐antitrypsin in fibrin clots
Publication Title: Journal of Thrombosis and Haemostasis -
Description Patients included in cohort. ICD‐9‐CM, International Classification of Diseases, Ninth Revision, Clinical Modification code.
Article Title: Prevalence of immune thrombocytopenia: analyses of administrative data
Publication Title: Journal of Thrombosis and Haemostasis -
Description Binding of human mAbs to beta2 glycoprotein‐1 (β2GP1). (A) Comparison of binding to full‐length β2GP1 (left) and domain I (right) between single chain Fv (scFv) fragments presented on phage...
Article Title: Patient‐derived monoclonal antibodies directed towards beta2 glycoprotein‐1 display lupus anticoagulant activity
Publication Title: Journal of Thrombosis and Haemostasis -
Description Relationship between PECAM‐1 cleavage and platelet‐derived microparticle generation under high shear stress. Platelets were preincubated with 20 μg mL−1 of rA1 domain and 1 mmol L−1 Ca2+, and...
Article Title: Cleavage of platelet endothelial cell adhesion molecule‐1 (PECAM‐1) in platelets exposed to high shear stress
Publication Title: Journal of Thrombosis and Haemostasis -
Description Mutation of the C‐terminal N‐linked glycan sites of ADAMTS‐13 (AD13) modulate proteolytic function. (A) Recombinant AD13 N‐linked glycan mutants N707Q, N828Q, N1235Q and N1354Q (final concentration...
Article Title: ADAMTS‐13 glycans and conformation‐dependent activity
Publication Title: Journal of Thrombosis and Haemostasis
Displaying assets 1 - 30 of 4980 in total. Search results limited to 100 out of 166 pages. Please refine your search query.