Asset Search
Displaying assets 1 - 30 of 1437 in total.
-
Description The effect of prenatal stress and antidepressant drugs treatment (tianeptine—Tia, venlafaxine—Ven, or fluoxetine—Flu) on the levels of CCL2 (ng/mg of protein) and its receptor—CCR2 (pg/mg of...
Article Title: Role of Chronic Administration of Antidepressant Drugs in the Prenatal Stress-Evoked Inflammatory Response in the Brain of Adult Offspring Rats: Involvement of the NLRP3 Inflammasome-Related Pathway
Publication Title: Molecular Neurobiology -
Description Effect of 4-PSQ treatment on the neural cell adhesion molecule (NCAM) levels in the cerebral cortex (a) and hippocampus (b) of rats. Values are expressed as mean ± standard error of the mean (n = 7...
Article Title: 7-Chloro-4-(Phenylselanyl) Quinoline with Memory Enhancer Action in Aging Rats: Modulation of Neuroplasticity, Acetylcholinesterase Activity, and Cholesterol Levels
Publication Title: Molecular Neurobiology -
Description Culture characterization. Culture purity assessment through immunocytochemistry using a to b microglial markers Griffonia simplicifolia (green) and CD11b (red); d to f oligodendroglial cell markers...
Article Title: Transferrin Enhances Microglial Phagocytic Capacity
Publication Title: Molecular Neurobiology -
Description In vitro propagation of misfolded prion proteins. a Ovine (OvDawson rec-PrPres, OvLanglade rec-PrPres, OvUKA2 rec-PrPres, OvSc21 rec-PrPres, OvBSE rec-PrPres, OvBSE-H rec-PrPres, and OvBSE-L...
Article Title: Insights into the Bidirectional Properties of the Sheep–Deer Prion Transmission Barrier
Publication Title: Molecular Neurobiology -
Description PK-resistant fragments of PrP are detected in terminally ill, but not in pre-symptomatic mice. Western blot of hippocampal proteins from infected samples and from age-matched controls, digested (+)...
Article Title: Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases
Publication Title: Molecular Neurobiology -
Description Possible mechanism of action for anti-Alzheimer’s action of Clitoria ternatea extracts. Binding of LPS to TLR causes the generation of ROS from NADPH oxidase and mitochondria. This generated ROS...
Article Title: Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology
Publication Title: Molecular Neurobiology -
Description Immunofluorescent quantification of EdU labelling in (A) isolated microglia, (B) mixed population microglia, and (C) representative confocal images. Cells were quantified by positive counts....
Article Title: In Vitro Priming and Hyper-Activation of Brain Microglia: an Assessment of Phenotypes
Publication Title: Molecular Neurobiology -
Description a Technical variations in individual TLDA card processing. Correlation matrix plot for ten individual RT and pre-amplification reactions on pooled CSF RNA. Group 1 (G1) and group 2 (G2) were...
Article Title: Analytics of Cerebrospinal Fluid MicroRNA Quantitative PCR Studies
Publication Title: Molecular Neurobiology -
Description Sodium butyrate has no effect on cell proliferation in SVZ after HI. Neonatal HI was induced at postnatal day 7. SB was administered directly after the onset of HI and for five consecutive days....
Article Title: Effect of the HDAC Inhibitor, Sodium Butyrate, on Neurogenesis in a Rat Model of Neonatal Hypoxia–Ischemia: Potential Mechanism of Action
Publication Title: Molecular Neurobiology -
Description Effect of bilateral NMDA-induced excitotoxic OB lesions on odour discrimination expressed as the number of correct choices. Animals received bilateral NMDA (1.5 μl of a saline solution of 12 mg/ml,...
Article Title: Recovery of Olfactory Function After Excitotoxic Lesion of the Olfactory Bulbs Is Associated with Increases in Bulbar SIRT1 and SIRT4 Expressions
Publication Title: Molecular Neurobiology -
Description MiR-210 negatively regulates ISCU expression in vivo and in vitro. a miR-210 mimic (100 pmol) or scramble (Neg. Ctrl) was administered into the right hemisphere of P5 rat brain...
Article Title: MicroRNA-210 Downregulates ISCU and Induces Mitochondrial Dysfunction and Neuronal Death in Neonatal Hypoxic-Ischemic Brain Injury
Publication Title: Molecular Neurobiology -
Description Cellular localization of CB1R and GPR55. SH-SY5Y cells, transfected with CB1R (top left image) and GPR55 (bottom left image) fused to YFP protein and identified by its fluorescence properties...
Article Title: Targeting CB and GPR55 Endocannabinoid Receptors as a Potential Neuroprotective Approach for Parkinson’s Disease
Publication Title: Molecular Neurobiology -
Description Immunofluorescence assay for CB1 and CB2 cannabinoid receptors in chick embryonic (E7C2) retinal cell cultures. Double labeling experiments with anti-CB1 (green) (a (1), c (1)) and anti-Tuj-1 (red)...
Article Title: Cannabinoids Induce Cell Death and Promote P2X7 Receptor Signaling in Retinal Glial Progenitors in Culture
Publication Title: Molecular Neurobiology -
Description Schematic drawings of brain slices, emphasizing the target areas: CA1 region of the dorsal hippocampus (bregma − 1.06 to − 2.3) and dorsomedial prefrontal cortex (bregma 2.58 to 1.9). Each black...
Article Title: Hippocampus and Prefrontal Cortex Modulation of Contextual Fear Memory Is Dissociated by Inhibiting De Novo Transcription During Late Consolidation
Publication Title: Molecular Neurobiology -
Description Upregulation of miR-210 in primary cortical neurons in response to OGD/reoxygenation. a Rat primary cortical neurons were subjected to OGD or cultured in normal condition for 1.5 or 6 h. The level...
Article Title: MicroRNA-210 Downregulates ISCU and Induces Mitochondrial Dysfunction and Neuronal Death in Neonatal Hypoxic-Ischemic Brain Injury
Publication Title: Molecular Neurobiology -
Description Experimental designs. a Experiment 1 was designed to examine effects of epidermal growth factor receptor (EGFR) inhibitor (AG1478) on cerebral vasospasm after SAH. b Experiment 2 was designed to...
Article Title: Anti-vasospastic Effects of Epidermal Growth Factor Receptor Inhibitors After Subarachnoid Hemorrhage in Mice
Publication Title: Molecular Neurobiology -
Description The neuronal growth cone responds to both repulsive (red) and attractive (green) tropic cues secreted in the extracellular milieu. Changes in microtubule dynamics cause extension of the...
Article Title: Current Understanding of the Role of Neuronal Calcium Sensor 1 in Neurological Disorders
Publication Title: Molecular Neurobiology -
Description Resveratrol protected blood–brain barrier (BBB) integrity and inhibited neuroinflammation after ischemic stroke. a Tissue concentrations of evans blue leaking into the ischemic (ipsilateral) cortex...
Article Title: Neuroprotection of Resveratrol Against Focal Cerebral Ischemia/Reperfusion Injury in Mice Through a Mechanism Targeting Gut-Brain Axis
Publication Title: Cellular and Molecular Neurobiology -
Description A Western blots of retinal lysates from younger and older, WT and APP/PS1 mice were probed with Cathepsin B. The relative intensities of WB bands were quantified and plotted (n = 3). B...
Article Title: Upregulation of Proteolytic Pathways and Altered Protein Biosynthesis Underlie Retinal Pathology in a Mouse Model of Alzheimer’s Disease
Publication Title: Molecular Neurobiology -
Description Labeling patterns of selected glycolytic, pentose phosphate, and first-turn TCA cycle intermediates following metabolism of [U-13C]glucose. 13C-labeled carbons are shown as black circles while...
Article Title: Impaired Pentose Phosphate Pathway in the Spinal Cord of the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis
Publication Title: Molecular Neurobiology -
Description Bioinformatic analysis by IPA of the proteins differentially expressed in the comparison OligoGM1 vs CONTROL N2a cells
Article Title: The Neuroprotective Role of the GM1 Oligosaccharide, IINeu5Ac-Gg, in Neuroblastoma Cells
Publication Title: Molecular Neurobiology -
Description β-Catenin haploinsufficiency caused increased HO1 immunoreactivity in SN after PQ treatment. Fixed brains of PQ or saline-treated Cre+ and Cre− mice were immunostained for HO1. Representative...
Article Title: Conditional Haploinsufficiency of β-Catenin Aggravates Neuronal Damage in a Paraquat-Based Mouse Model of Parkinson Disease
Publication Title: Molecular Neurobiology -
Description Effects of DOR activation/inhibition on inflammatory cytokine protein expressions in cerebellar tissues under HI. Expression levels of TNF-α, IL-6, ICAM-1, IL-10, and IL-18 in cerebellar tissues...
Article Title: δ-Opioid Receptor-Nrf-2-Mediated Inhibition of Inflammatory Cytokines in Neonatal Hypoxic-Ischemic Encephalopathy
Publication Title: Molecular Neurobiology -
Description Pilocarpine-induced brain damage in the pioglitazone and DMSO groups. (a, Nissl staining) Twenty-four hours after status epilepticus was induced, the severity of neuronal loss, and the number of...
Article Title: The Protective Role of Peroxisome Proliferator-Activated Receptor-Gamma in Seizure and Neuronal Excitotoxicity
Publication Title: Molecular Neurobiology -
Description Signature of four miRNAs associated with SCA7 phenotype. a The best number of genes that lead to the smallest error rate in the class prediction model had been identified N = 4, as shown in the...
Article Title: Wide Profiling of Circulating MicroRNAs in Spinocerebellar Ataxia Type 7
Publication Title: Molecular Neurobiology -
Description Sexual behavior in WT (n = 9), WT-HFD (n = 5), MC4RKO (n = 9), and tbMC4RSim1 (n = 10) mice. a WT-HFD mice were weight-matched to MC4RKO mice and both groups weighed significantly more than WT...
Article Title: Oxytocin Neurons Enable Melanocortin Regulation of Male Sexual Function in Mice
Publication Title: Molecular Neurobiology -
Description Putative mechanisms of the preventive effects of Rg1 against chemobrain induced by DAC
Article Title: Ginsenoside Rg1 Prevents Chemotherapy-Induced Cognitive Impairment: Associations with Microglia-Mediated Cytokines, Neuroinflammation, and Neuroplasticity
Publication Title: Molecular Neurobiology -
Description The synergistic cytotoxic effect of the combined therapy of ASA (24 h, 10 mM) and JS-K (6 h, 1–15 μM) compared to JS-K alone was determined by the MTT viability assay for primary IC cells (a),...
Article Title: Cyclooxygenase (COX) Inhibition by Acetyl Salicylic Acid (ASA) Enhances Antitumor Effects of Nitric Oxide in Glioblastoma In Vitro
Publication Title: Molecular Neurobiology -
Description Reproductive hormone levels in MC4RKO mice and re-expression models. a Serum testosterone, b estradiol, c LH, and d FSH, and e the LH:FSH ratio concentrations were not different using a one-way...
Article Title: Oxytocin Neurons Enable Melanocortin Regulation of Male Sexual Function in Mice
Publication Title: Molecular Neurobiology -
Description Changes in brain sphingolipid metabolism and signaling observed in Alzheimer’s disease.Human postmortem brain material was used by numerous authors to compare the levels of bioactive sphingolipids,...
Article Title: The Role of Ceramide and Sphingosine-1-Phosphate in Alzheimer’s Disease and Other Neurodegenerative Disorders
Publication Title: Molecular Neurobiology
Displaying assets 1 - 30 of 1437 in total.