Description Characteristics of APE1‐overexpressing CPCs. (A): Exogenous human APE1 levels as determined by RT‐PCR; expression was detected in APE1‐CPCs but not control‐CPCs. There was no difference in the...
Article Title: Apoptosis‐Resistant Cardiac Progenitor Cells Modified With Apurinic/Apyrimidinic Endonuclease/Redox Factor 1 Gene Overexpression Regulate Cardiac Repair After Myocardial Infarction
Publication Title: STEM CELLS Translational Medicine

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Description Cytokines and growth factors in mouse BAL at 24 hours
Article Title: Activation of Human Mesenchymal Stem Cells Impacts Their Therapeutic Abilities in Lung Injury by Increasing Interleukin (IL)‐10 and IL‐1RN Levels
Publication Title: STEM CELLS Translational Medicine

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Description Activation of HOXB4 resulted in a modest increase in the proportion of immature CD235a+/CD71+ erythroid cells. HOXB4 was activated with 4OHT from days 10 to 24 (A). Production of erythroid cells...
Article Title: Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells
Publication Title: STEM CELLS Translational Medicine

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Description Small molecule‐based differentiation protocol promotes eye‐field induction. (A): Schematic diagram showing the timeline of retinal differentiation of human pluripotent cells. DIN represents the...
Article Title: Generation of Transplantable Retinal Photoreceptors from a Current Good Manufacturing Practice‐Manufactured Human Induced Pluripotent Stem Cell Line
Publication Title: STEM CELLS Translational Medicine

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Description The specific miRNAs from uMSC‐Exo contributed to the antiviral activity on HCV infection. (A): Purified uMSC‐Exo were subjected to PuMSC‐Exo for indicated time durations (15 minutes or 60 minutes),...
Article Title: Exosomal MicroRNAs Derived From Umbilical Mesenchymal Stem Cells Inhibit Hepatitis C Virus Infection
Publication Title: STEM CELLS Translational Medicine

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Description Intervertebral disc (IVD) herniation. Representative sections of the hernia for the following groups: puncture (A), saline (B), rMSC (C), and rFb (D), showing proteoglycan‐rich extracellular matrix...
Article Title: Systemic Delivery of Bone Marrow Mesenchymal Stem Cells for In Situ Intervertebral Disc Regeneration
Publication Title: STEM CELLS Translational Medicine

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Description Immunomodulatory potency of amnion epithelial cell‐derived exosomes. Neutrophil myeloperoxidase (MPO) production was significantly reduced in the presence of both hAEC [1 μg; p = .022 and 5 μg; p =...
Article Title: Amnion Epithelial Cell‐Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair
Publication Title: STEM CELLS Translational Medicine

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Description Porcine MSC characterization. (A): Morphology at P1. (B): Proliferative capacity. (C): Clonogenicity. (D): Phenotype. (E): Differentiation. (F): Protein synthesis and secretion capacity of porcine...
Article Title: Repeated Autologous Bone Marrow‐Derived Mesenchymal Stem Cell Injections Improve Radiation‐Induced Proctitis in Pigs
Publication Title: STEM CELLS Translational Medicine

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Description Stagewise human embryonic stem cell (hESC) differentiation to the hepatocyte lineage. (A): Phase‐contrast imaging demonstrated that cells underwent sequential morphological changes during transit...
Article Title: Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs
Publication Title: STEM CELLS Translational Medicine

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Description Cell tracking in rats treated with stromal vascular fraction (SVF). (A, B): Percentages of CM‐DiI‐positive areas in kidney sections of rats at 24 (A) and 72 (B) hours after IR were calculated....
Article Title: Preischemic Administration of Nonexpanded Adipose Stromal Vascular Fraction Attenuates Acute Renal Ischemia/Reperfusion Injury and Fibrosis
Publication Title: STEM CELLS Translational Medicine

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Description Chemotaxis and proliferation. (A): Migration assay. Medium from neonatal human cardiac progenitor cells (hCPCs) induces migration of mesenchymal stem cells (MSCs). Human MSCs were incubated in a...
Article Title: Age‐Dependent Effect of Pediatric Cardiac Progenitor Cells After Juvenile Heart Failure
Publication Title: STEM CELLS Translational Medicine

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Description Endothelial progenitor cell extract reduces fibrosis in UUO kidney. EPC extract was injected subcapsularly, as detailed in Materials and Methods. (A): Renal histology on day 14 in vehicle‐treated...
Article Title: Instructive Role of the Microenvironment in Preventing Renal Fibrosis
Publication Title: STEM CELLS Translational Medicine

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Description Mesenchymal stem cell‐derived MMP‐2 accelerates degradation of α‐synuclein fibrils. (A): An electron microscopy analysis showed that α‐synuclein (αS) aggregates in the presence of MMP‐2 exhibited a...
Article Title: The Cleavage Effect of Mesenchymal Stem Cell and Its Derived Matrix Metalloproteinase‐2 on Extracellular α‐Synuclein Aggregates in Parkinsonian Models
Publication Title: STEM CELLS Translational Medicine

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Description Immunogenicity of peptides in vivo. Cytotoxic CD8+ T cell lines were generated from splenocytes from mice immunized with CD133 peptides, Mart1a/Flu‐HA, or PBS only. After 7 days of in vitro...
Article Title: Identification of Novel Human Leukocyte Antigen‐A*0201‐Restricted, Cytotoxic T Lymphocyte Epitopes on CD133 for Cancer Stem Cell Immunotherapy
Publication Title: STEM CELLS Translational Medicine

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Description Expression of differentiation neural markers by normal (hNSC), v‐myc‐immortalized (IhNSC), and human glioblastoma (hGBM)‐derived stem‐like cells. hNSCs, IhNSCs, and hGBM‐derived stem‐like cells...
Article Title: Concise Review: Self‐Renewal in the Central Nervous System: Neural Stem Cells from Embryo to Adult
Publication Title: STEM CELLS Translational Medicine

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Description Neutrophil engraftment curve by the combination of HLA‐haplotypes. Cumulative incidence curve was assessed using the competing risk regression method with adjustment for the confounders described...
Article Title: Risk of HLA Homozygous Cord Blood Transplantation: Implications for Induced Pluripotent Stem Cell Banking and Transplantation
Publication Title: STEM CELLS Translational Medicine

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Description Isogenic mASCsdb−/db− and mASCWT increase angiogenesis in diabetic defects. (A): Blood vessels and endothelial cells were detected by immunofluorescence for PECAM‐1 (3 dpo). db−/db− control mice...
Article Title: Local Application of Isogenic Adipose‐Derived Stem Cells Restores Bone Healing Capacity in a Type 2 Diabetes Model
Publication Title: STEM CELLS Translational Medicine

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Description Flow chart of the study protocol. *2 rats died presumably due to anesthesia complication. Abbreviations: hASCs, human adipose stem cells; μCT, micro‐computed tomography; NaCl, sodium chloride.
Article Title: Functional Outcome of Human Adipose Stem Cell Injections in Rat Anal Sphincter Acute Injury Model
Publication Title: STEM CELLS Translational Medicine

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Description In vitro coculture of engineered cartilage and activated macrophage for 24 hours. (A): Coculturing of different groups of engineered cartilage with macrophages in a transwell system. (B, C):...
Article Title: Bone Marrow Mesenchymal Stem Cell‐Based Engineered Cartilage Ameliorates Polyglycolic Acid/Polylactic Acid Scaffold‐Induced Inflammation Through M2 Polarization of Macrophages in a Pig Model
Publication Title: STEM CELLS Translational Medicine

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Description Impaired activation of Wnt signaling in CD133‐Kd lines. (A, B): Quantitative real‐time PCR showing the expression of WNT4 upon cisplatin induced damage (A) or stimulation with CHIR99021 (B) by...
Article Title: Role of CD133 Molecule in Wnt Response and Renal Repair
Publication Title: STEM CELLS Translational Medicine

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Description Morphologic appearance of BMSCs in culture supplemented with various growth factors. (A): Representative phase‐contrast images showing the change of BMSC morphology under different treatments at...
Article Title: Stepwise Differentiation of Mesenchymal Stem Cells Augments Tendon‐Like Tissue Formation and Defect Repair In Vivo
Publication Title: STEM CELLS Translational Medicine

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Description Characterization of stimulation‐induced action potential firing of neurons derived from baboon fibroblast‐derived induced pluripotent stem cells (biPSCs). (A): Representative current clamp...
Article Title: Differentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells
Publication Title: STEM CELLS Translational Medicine

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Description Effect of uMSC‐Exo on different stages of hepatitis C virus (HCV) infection. (A): Human dermal fibroblast 7 (Huh7) cells were infected with cell‐derived HCV of JFH‐1 for 4 hours before the medium...
Article Title: Exosomal MicroRNAs Derived From Umbilical Mesenchymal Stem Cells Inhibit Hepatitis C Virus Infection
Publication Title: STEM CELLS Translational Medicine

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Description Potency: outline of benchmark
Article Title: Adapting Preclinical Benchmarks for First‐in‐Human Trials of Human Embryonic Stem Cell‐Based Therapies
Publication Title: STEM CELLS Translational Medicine

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Description Mesenchymal stem cell (MSC) spheroids entrapped in RGD‐modified alginate hydrogels have increased survival and proangiogenic potential compared with dissociated MSCs. (A): Total DNA content in gel...
Article Title: Increased Survival and Function of Mesenchymal Stem Cell Spheroids Entrapped in Instructive Alginate Hydrogels
Publication Title: STEM CELLS Translational Medicine

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Description Digit tip regeneration. Unamputated: The mouse terminal phalanx (P3), is a triangular shaped cortical bone; wide at its base where it articulates with the second phalanx (P2; not pictured),...
Article Title: Digit Tip Regeneration: Merging Regeneration Biology with Regenerative Medicine
Publication Title: STEM CELLS Translational Medicine

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Description Distant injection of 4T1 cells and mesenchymal stem cells (MSCs) before tumor cell inoculation inhibited tumor growth. Distant injection of 4T1 cells and MSCs also inhibited tumor growth when using...
Article Title: Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth
Publication Title: STEM CELLS Translational Medicine

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Description Improvement in the tissue structures of the liver, adipose, and pancreas in db/db mice (scale bars = 100 µm). (A): Hematoxylin and eosin staining of representative liver, adipose, and pancreas...
Article Title: Adipose‐Derived Mesenchymal Stem Cells Ameliorate Lipid Metabolic Disturbance in Mice
Publication Title: STEM CELLS Translational Medicine

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Description Pluripotency characterization of WBS iPS cells (line B). (A): iPS cells stained positive for pluripotency markers NANOG, OCT4, and SSEA4. (B): Flow cytometry analysis of SSEA4. (C): WBS‐iPS...
Article Title: Modeling and Rescue of the Vascular Phenotype of Williams‐Beuren Syndrome in Patient Induced Pluripotent Stem Cells
Publication Title: STEM CELLS Translational Medicine

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Description Expression of W5C5, CD271, TNAP, and CD344 in leiomyosarcoma and rhabdomyosarcoma. Sarcomas with smooth and striated muscle morphology are shown side by side as follows: the human LMS cell line...
Article Title: Shared Cell Surface Marker Expression in Mesenchymal Stem Cells and Adult Sarcomas
Publication Title: STEM CELLS Translational Medicine

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