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Description Meiosis and zygosity outcomes during parthenogenesis. (A): Normal fertilization with sperm. During the prophase I of meiosis I, the two parental chromosomes (depicted as white and black), each...
Article Title: Concise Review: Parthenote Stem Cells for Regenerative Medicine: Genetic, Epigenetic, and Developmental Features
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016591238-fig-0003
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Survival of osteoblasts and osteoblast progenitors in recipient bone marrow. (A–C): Representative toluidine blue‐staining images exhibiting osteoblasts (black arrows). Unstained empty spaces...
Article Title: Allogeneic Mesenchymal Stem Cell Therapy Promotes Osteoblastogenesis and Prevents Glucocorticoid‐Induced Osteoporosis
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312109-fig-0004
- License Type
- CC-BY
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Magnetic resonance angiograms (left: baseline; right: 6 month) of one patient (ID number 08016) in the group receiving 2 million cells/kg body weight. Angiograms show overall increase in the...
Article Title: Administration of Adult Human Bone Marrow‐Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells in Critical Limb Ischemia Due to Buerger’s Disease: Phase II Study Report Suggests Clinical Efficacy
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312276-fig-0003
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Molecular effects of cisplatin on CD133‐Kd cells. (A): Signaling pathways over‐represented by the 102 genes differentially expressed in shPROM1 in respect to CD133+ control cells after cisplatin...
Article Title: Role of CD133 Molecule in Wnt Response and Renal Repair
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016591257-fig-0005
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description iPSC hepatocytes express a higher degree of maturity and albumin synthesis within ECM scaffolds. Graphs show albumin production (A), AFP biosynthesis (B), and albumin/AFP protein synthesis ratio...
Article Title: Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312246-fig-0006
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Vascular density in the border zone 21 days post‐myocardial infarction. (A): Confocal image of representative immunofluorescent staining (×60). Endothelial cell staining with isolectin (green)....
Article Title: Role of SDF‐1:CXCR4 in Impaired Post‐Myocardial Infarction Cardiac Repair in Diabetes
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312284-fig-0001
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Leukemic stem cells (LSCs) and potential targets of drug therapy.
Article Title: Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment
Publication Title: STEM CELLS Translational Medicine -
Description Characterization of RPE generated from human embryonic stem cells (hESC‐RPE) derived on Synthemax II‐SC. (A): Phase‐contrast and bright‐field images show the typical pigmentation and cobblestone...
Article Title: Defined Culture of Human Embryonic Stem Cells and Xeno‐Free Derivation of Retinal Pigmented Epithelial Cells on a Novel, Synthetic Substrate
Publication Title: STEM CELLS Translational Medicine -
Description Histological stage of hepatic fibrosis
Article Title: Effect of Function‐Enhanced Mesenchymal Stem Cells Infected With Decorin‐Expressing Adenovirus on Hepatic Fibrosis
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016581067-fig-0002
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description H2O2‐induced ROS production and apoptosis in CPCs via activation of TAK1/NF‐κB signaling. (A): Graph of dichloro‐dihydro‐fluorescein diacetate concentration (ROS production) after H2O2 treatment...
Article Title: Apoptosis‐Resistant Cardiac Progenitor Cells Modified With Apurinic/Apyrimidinic Endonuclease/Redox Factor 1 Gene Overexpression Regulate Cardiac Repair After Myocardial Infarction
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32013211862-fig-0004
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Triple lineage differentiation of expanded neural stem cells derived from H9 embryonic stem cells. (A–C): Differentiated cells were stained with antibodies against the neuronal marker βIII tubulin...
Article Title: Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells
Publication Title: STEM CELLS Translational Medicine -
Description Selected key clinical studies using mesenchymal stem cells for the treatment of wounds
Article Title: Concise Review: Role of Mesenchymal Stem Cells in Wound Repair
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312004-tbl-0006
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Quality‐of‐life indicators
Article Title: Combined Bone Marrow‐Derived Mesenchymal Stromal Cell Therapy and One‐Way Endobronchial Valve Placement in Patients with Pulmonary Emphysema: A Phase I Clinical Trial
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016591247-fig-0006
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Effects of decorin on TGF‐β/Smad signaling in HSCs. Western blot analysis of the levels of α‐SMA and phospho‐Smad3 in immortalized HSCs. (A): TGF‐β1‐induced changes after infection of HSCs with...
Article Title: Effect of Function‐Enhanced Mesenchymal Stem Cells Infected With Decorin‐Expressing Adenovirus on Hepatic Fibrosis
Publication Title: STEM CELLS Translational Medicine -
Description Expansion of established MAPC cultures in xeno‐free medium and on the Quantum bioreactor. (A): Proliferation represented as number of population doublings (PD) of established MAPCs, expanded under...
Article Title: Using miRNA‐mRNA Interaction Analysis to Link Biologically Relevant miRNAs to Stem Cell Identity Testing for Next‐Generation Culturing Development
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312004-tbl-0004
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Pulmonary function testing
Article Title: Combined Bone Marrow‐Derived Mesenchymal Stromal Cell Therapy and One‐Way Endobronchial Valve Placement in Patients with Pulmonary Emphysema: A Phase I Clinical Trial
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016581026-fig-0003
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Engineered HUCPVCs can produce therapeutically useful quantities of anti‐VEEV antibody in culture. Culture supernatants were harvested every 3–4 days from HUCPVCs engineered with the anti‐VEEV...
Article Title: Engineered Mesenchymal Cells Improve Passive Immune Protection Against Lethal Venezuelan Equine Encephalitis Virus Exposure
Publication Title: STEM CELLS Translational Medicine -
Description Target site prediction summary of top 15 abundant microRNAs in umbilical mesenchymal stem cell‐derived exosomes
Article Title: Exosomal MicroRNAs Derived From Umbilical Mesenchymal Stem Cells Inhibit Hepatitis C Virus Infection
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct320165111461-fig-0003
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description iPSC‐derived skeletal muscle cells express key myogenic genes at day 36. Myogenic genes PAX3, MYOG, MYOD1, CHRNA1, and MHC all revealed high expression levels compared with undifferentiated iPSCs....
Article Title: A Novel Protocol for Directed Differentiation of C9orf72‐Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32013211896-fig-0004
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Vascular density as evaluated through immunohistochemistry in MI, MI SVF, and MI Vicryl hearts. (A): Representative GS‐1+ staining indicating coronary vascular density in the infarct and...
Article Title: Adipose‐Derived Cell Construct Stabilizes Heart Function and Increases Microvascular Perfusion in an Established Infarct
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32013211884-tbl-0002
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Cytokines and growth factors in mouse BAL at 24 hours
Article Title: Activation of Human Mesenchymal Stem Cells Impacts Their Therapeutic Abilities in Lung Injury by Increasing Interleukin (IL)‐10 and IL‐1RN Levels
Publication Title: STEM CELLS Translational Medicine -
Description Pretreatment of MSCs enhances transmigration through the blood‐brain barrier (BBB). (A): Schematic of 8‐µm‐pore Transwell chamber coated with human brain microvascular endothelial cells (hBMECs)...
Article Title: Pre‐Exposure of Human Adipose Mesenchymal Stem Cells to Soluble Factors Enhances Their Homing to Brain Cancer
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016581036-fig-0001
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Epigenetic chemical compound library screen for the effect of 24 compounds on adipocytic differentiation of human skeletal (mesenchymal) stem cells (hMSCs). Representative Oil Red O staining of...
Article Title: Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312250-fig-0004
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description The redifferentiation of γδT‐iPSCs into hematopoietic lineage. (A): A schematic diagram showing the redifferentation protocol for deriving hematopoietic progenitor cells from γδT‐iPSCs. (B): The...
Article Title: The Generation of Human γδT Cell‐Derived Induced Pluripotent Stem Cells from Whole Peripheral Blood Mononuclear Cell Culture
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32013211862-fig-0007
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Heat map. (A): Expression of NSC‐related genes and default regional identity of the sample population shown by a heat map generated by the R software. NSCs from pluripotent stem cell (PSC) origin...
Article Title: Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells
Publication Title: STEM CELLS Translational Medicine -
Description Analyses of the bone marrow (BM) of NOD/SCIDs in different treatment groups. (A, B): Fluorescence‐activated cell sorting (FACS) analysis of BM aspirates at days 5 and 10, showing significantly...
Article Title: Bone Marrow Regeneration Promoted by Biophysically Sorted Osteoprogenitors From Mesenchymal Stromal Cells
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32016591238-fig-0002
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Bone formation and bone resorption parameters. (A–C): Representative calcein‐labeling images exhibiting bone formation rates. Mice received double injection of 20 mg/kg calcein at 16 and 2 d before...
Article Title: Allogeneic Mesenchymal Stem Cell Therapy Promotes Osteoblastogenesis and Prevents Glucocorticoid‐Induced Osteoporosis
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct312102-fig-0004
- License Type
- CC-BY
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Migration and differentiation of electromechanically conditioned cardiac adipose tissue‐derived progenitor cells (cardiac ATDPCs) in a mouse model of myocardial infarction. Immunofluorescence...
Article Title: Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32013211906-fig-0003
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Motor neuron differentiation in transplants induced by MesoMim. (A, B): HB9‐GFP+ motor neurons (MNs) 2 weeks (left) and 2 months (right) after transplantation of EBs to the dorsal root ganglion...
Article Title: Delivery of Differentiation Factors by Mesoporous Silica Particles Assists Advanced Differentiation of Transplanted Murine Embryonic Stem Cells
Publication Title: STEM CELLS Translational Medicine -
- Identifier
- sct32013211884-fig-0001
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Protective effect of different hMSCs at 24 hours. (A): Experimental design. (B, C): Lung hematoxylin and eosin staining for saline (B) and hMSC8 (C). Magnification, ×10. Scale bars = 500 μm. (D–G):...
Article Title: Activation of Human Mesenchymal Stem Cells Impacts Their Therapeutic Abilities in Lung Injury by Increasing Interleukin (IL)‐10 and IL‐1RN Levels
Publication Title: STEM CELLS Translational Medicine