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Displaying assets 1 - 30 of 60914 in total. Search results limited to 100 out of 2031 pages. Please refine your search query.
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Description Ablation of E‐cadherin in back skin epidermis and in hair follicles of mutant mice. Epidermis of back skin of P15 control (A) and mutant (B) mice shows a reduction of E‐cadherin immunoreactivity in...
Article Title: E‐cadherin controls adherens junctions in the epidermis and the renewal of hair follicles
Publication Title: The EMBO Journal -
Description Induced fit in mCD1d upon NU‐α‐GalCer binding. (A) Superposition of the α1 and α2 helix backbones of CD1d in the four ternary structures. α‐GalCer, cyan; NU‐α‐GalCer, yellow; BnNH‐GSL‐1′, green and...
Article Title: Galactose‐modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis
Publication Title: The EMBO Journal -
Description Regulatory networks in the control of vascular stem cell activities.
Article Title: Stem cell function during plant vascular development
Publication Title: The EMBO Journal -
Description The BH3 domain of Hrk is required for the induction of cell death. (A) 293T cells (1.7×106 per 35 mm plate) were transfected with 0.3 μg of pRK7.GFP and 0.8 μg of pCDNA3 (control), 0.8 μg of...
Article Title: harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival‐promoting proteins Bcl‐2 and Bcl‐XL
Publication Title: The EMBO Journal -
Description Expression of the targeted ephA8/eek gene in E10.5 embryos. (A) Whole mount X‐gal staining of (+/−) and (−/−) E10.5 embryos. LacZ expression is seen in the midbrain tectum (t), hindbrain (hb),...
Article Title: Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors
Publication Title: The EMBO Journal -
Description SAPK4 is activated by cytokines and cellular stresses in KB cells. KB cells were transiently transfected with a DNA construct encoding myc epitope‐tagged SAPK4, as indicated in Materials and...
Article Title: Activation of the novel stress‐activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
Publication Title: The EMBO Journal -
Description Domain structure of Munc13‐1 and ubMunc13‐2. The CaM‐binding domains are highlighted in green. The expansion shows the primary sequence alignment of these CaM‐binding domains with peptides...
Article Title: Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short‐term synaptic plasticity
Publication Title: The EMBO Journal -
Description Structures of PPADS and bifunctional PPADS analogues.
Article Title: P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand‐gated ion channels
Publication Title: The EMBO Journal -
Description Stereoview of a superposition of the 20 lowest energy structures of SAP/SH2D1A–SLAM peptide complexes (using backbone atoms of residues 6–56). The protein (residues 6–104) is shown in blue for the...
Article Title: A ‘three‐pronged’ binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome
Publication Title: The EMBO Journal -
Description Northern blotting of pre‐edited, partially edited, and fully edited RPS12 mRNAs. Total RNA was separated on a 5% polyacrylamide/8 M urea gel and sequentially hybridized with radiolabeled...
Article Title: PPR polyadenylation factor defines mitochondrial mRNA identity and stability in trypanosomes
Publication Title: The EMBO Journal -
Description Oleate incorporation into sterol esters. Cells were pulsed with [3H]oleic acid and dried. Lipids were extracted with hexane and separated by thin‐layer chromatography (TLC). Oleate incorporation...
Article Title: AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism
Publication Title: The EMBO Journal -
Description Heat‐denatured luciferase binds to HSP18.1 and is competent for refolding. In (A), 1 μM firefly luciferase was incubated with 1 μM HSP18.1 for 15 min at 22 or 42°C, and analyzed by SEC as described...
Article Title: A small heat shock protein stably binds heat‐denatured model substrates and can maintain a substrate in a folding‐competent state
Publication Title: The EMBO Journal -
- Identifier
- embj201797537-fig-0006
- License Type
- CC-BY
- Rights Holder
- Rights Managed by John Wiley & Sons
Description ARegulatory T cells (Tregs; CD4+Foxp3+) and induced Tregs (iTregs; Nrp1−) in the mLN from CD1d−/− and CD1d+/− mice. Flow cytometry plots (top) and frequency and numbers of Treg and iTreg (bottom)...
Article Title: CD1d‐mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis
Publication Title: The EMBO Journal -
Description (A) Sequence alignment of Dbp5p homologues. Protein sequences of Dbp5p (S.cerevisiae) homologues found in S.pombe, Mus musculus and D.discoideum were aligned using the PILEUP program in the GCG...
Article Title: Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export
Publication Title: The EMBO Journal -
Description Uri1p interacts with proteins involved in protein quality control. (A) Co‐immunoprecipitation assays with endogenously tagged Uri1p‐interacting proteins. TAP‐tagged Pfd6p (YAD349), Ssb1p (YAD155),...
Article Title: Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control
Publication Title: The EMBO Journal -
Description Dynamics of Sir3 binding and histone modifications at HMR. (A) Time course of Sir3 binding to Chr3. Log2 (Sir3/IP input) values were obtained from anti‐HA immunoprecipitation from THC70 cells after...
Article Title: Dynamics of Sir3 spreading in budding yeast: secondary recruitment sites and euchromatic localization
Publication Title: The EMBO Journal -
Description Kinetics of hamster GPI(–) PrP cell‐free conversion. The rate of [35S]PrP‐res formation was determined for both PPS‐stimulated and non‐stimulated control cell‐free conversion reactions over 96 h....
Article Title: Sulfated glycans and elevated temperature stimulate PrPSc‐dependent cell‐free formation of protease‐resistant prion protein
Publication Title: The EMBO Journal -
Description Interaction of TR3 with p53 promotes MDM2 self‐degradation. (A) Subcellular localization of TR3, p53, and MDM2 in 293 cells. Myc‐TR3, GFP‐p53, and/or HA‐MDM2 were transfected into cells as...
Article Title: p53 mediates the negative regulation of MDM2 by orphan receptor TR3
Publication Title: The EMBO Journal -
Description glide/gcm activates transcription from the glide/gcm promoter in vitro. (A) A reporter construct containing 6.5 kb of glide/gcm promoter sequence (WT‐CAT6) was tested for transactivation potential...
Article Title: Positive autoregulation of the glial promoting factor glide/gcm
Publication Title: The EMBO Journal -
Description Induction of nrtA, niaD and niiA transcripts in wild type (WT) and the double mutant nrtA747 nrtB110. Total RNA was isolated from mycelium grown at 37°C in minimal medium for 6 h with 10 mM proline...
Article Title: Apparent genetic redundancy facilitates ecological plasticity for nitrate transport
Publication Title: The EMBO Journal -
Description Effect of dephosphorylation on RAP46 interactions. [35S]methionine‐labeled, in vitro‐synthesized proteins were either treated with alkaline phosphatase (see Materials and methods) or not, as...
Article Title: Mammalian protein RAP46: an interaction partner and modulator of 70 kDa heat shock proteins
Publication Title: The EMBO Journal -
- Identifier
- embj2008176-fig-0010
- License Type
- CC-BY-NC-SA
- Rights Holder
- Rights Managed by John Wiley & Sons
Description PVM localisation of Irgm2 and Irgm3 is dependent on other IRG proteins and nucleotide. gs3T3 cells infected with T. gondii. Parasites were detected with αGRA7 mAb (E, green), αT. gondii rabbit (H,...
Article Title: Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
Publication Title: The EMBO Journal -
Description Behavioral analysis of Fgfr1 midbrain–hindbrain mutants
Article Title: FGFR1 is independently required in both developing mid‐ and hindbrain for sustained response to isthmic signals
Publication Title: The EMBO Journal -
Description Illustration showing the experimental approach to probe total and aggregate FTTTRA25T in conditioned media prepared on cells overexpressing FTTTRA25T and ERdj3 variants. Conditioned media was...
Article Title: The endoplasmic reticulum HSP40 co‐chaperone ERdj3/DNAJB11 assembles and functions as a tetramer
Publication Title: The EMBO Journal -
Description Autoradiograms of a northern blot of total RNA isolated from newborn rat tissues hybridized with 32P‐nick‐translated ruk and L27 probes showing the relative levels of expression of ruk mRNAs in...
Article Title: Negative regulation of PI 3‐kinase by Ruk, a novel adaptor protein
Publication Title: The EMBO Journal -
Description Identification of lens proteins that associate with the γEt‐crystallin and γBnop‐crystallin nuclear deposits. (A) E17.5 Crygenop lenses were stained with polyclonal rabbit antibodies to CP49 (green...
Article Title: Altered aggregation properties of mutant γ‐crystallins cause inherited cataract
Publication Title: The EMBO Journal -
Description Knockdown of lncRNA‐JADE inhibits mammary tumour growth in vivo. (A) Higher levels of lncRNA‐JADE in human breast cancer tissues in comparison with normal breast tissues. In situ hybridization of...
Article Title: A novel non‐coding RNA lncRNA‐JADE connects DNA damage signalling to histone H4 acetylation
Publication Title: The EMBO Journal -
Description Putative caspase cleavage sites in Bcl‐2 and Bax showing the epitopes of all antibodies described in this study.
Article Title: Alphaviruses induce apoptosis in Bcl‐2‐overexpressing cells: evidence for a caspase‐mediated, proteolytic inactivation of Bcl‐2
Publication Title: The EMBO Journal -
Description A simplified model that describes the conformations and equilibria involved in AcP amyloid formation in vitro. The native state is less prone to aggregation because intramolecular interactions...
Article Title: Mutational analysis of the propensity for amyloid formation by a globular protein
Publication Title: The EMBO Journal -
Description Differential scanning calorimetry profiles of excess specific heat (Cp) versus temperature for control SOD dimer (–––) and permuted β‐strand forms SOD N−1, C+1 (– – –), SOD N−2, C+2 (…) and SOD...
Article Title: Function of the Greek key connection analysed using circular permutants of superoxide dismutase
Publication Title: The EMBO Journal
Displaying assets 1 - 30 of 60914 in total. Search results limited to 100 out of 2031 pages. Please refine your search query.