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Displaying assets from 1 to 30 out of 21471
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- fsb2fj055495com-fig-0002-m
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- John Wiley & Sons, Inc.
Description Proteasome inhibitors impair ribosome function. A) Polyribosome content is not altered after 3 h treatment with 1 μM MG262 or epoxomycin. B) Administration of 1 μM MG262 or epoxomycin directly to...
Article Title: Proteasome inhibition induces reversible impairments in protein synthesis
Publication Title: The FASEB Journal -
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- fsb2fj09132225-fig-0001-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Mouse model of mild vascular injury. A) Partial endothelial denudation of carotid artery. Representative carotid artery sections 1 d after mild wire injury or sham surgery in wild‐type (C57BL6/J)...
Article Title: Bone marrow‐derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction
Publication Title: The FASEB Journal -
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- fsb2fj000625fje-fig-0007-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Representative tracing of [Ca++]I in cultured AC exposed to 24 h of hypoxia. 100 nM ET‐1 triggers a [Ca++]I transient comparable with that induced by 100 µM ATP.
Article Title: Hypoxia reverses dibutyryl‐cAMP‐induced stellation of cultured astrocytes via activation of the endothelin system
Publication Title: The FASEB Journal -
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- fsb2fj10169789-fig-0007-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Anti‐PECAM/SOD blocks TLR3‐mediated endothelial cell activation by poly(I:C). A) Effect of antioxidant enzymes on poly(I:C) activation of VCAM protein level determined by Western blotting. B)...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
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- fsb2fj010032com-fig-0005-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description A) Percentage of lumen restenosis after vessel injury in control (dotted bar), Ad‐βgal‐treated (vertical lanes bar), or mp21WAF/CIP1‐treated (horizontal lanes bar) apoE arteries, respectively. B)...
Article Title: Mutated p21/WAF/CIP transgene overexpression reduces smooth muscle cell proliferation, macrophage deposition, oxidation‐sensitive mechanisms, and restenosis in hypercholesterolemic apolipoprotein E knockout mice
Publication Title: The FASEB Journal -
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- fsb2fj09152728-fig-0005-m
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- John Wiley & Sons, Inc.
Description Quantitation of MitoSOX staining by flow cytometry and oxidation of lipids and proteins in CoQ10‐deficient skin fibroblasts and controls after 48 h in galactose medium with regular FBS (A–C) or...
Article Title: Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency
Publication Title: The FASEB Journal -
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- fsb2fj10155614-fig-0005-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Dynamic light‐scattering profiles of different CaM‐SPC solutions in case of Ca2+CaM (A) and apoCaM (B). Symbols represent 500 µM SPC (×), 40 µMCa2+CaM (▲), 40 µM apoCaM (Δ), 200 µM SPC with 8...
Article Title: Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid‐protein interactions
Publication Title: The FASEB Journal -
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- fsb2fj000440com-fig-0005-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description IE63‐positive neuron, labeled after recording. The neuron showed sensitivity to norepinephrine and a rise in intracellular calcium concentration (right panel). The cell was loaded with FURA‐2/AM...
Article Title: Infection by human varicella‐zoster virus confers norepinephrine sensitivity to sensory neurons from rat dorsal root ganglia
Publication Title: The FASEB Journal -
Description Liver consequences of the impaired food restriction response in CT‐1 null mice. A, Representatives images of H&E staining of liver tissues from fed (200×) and 48 hours food‐restricted animals...
Article Title: Cardiotrophin‐1 contributes to metabolic adaptations through the regulation of lipid metabolism and to the fasting‐induced fatty acid mobilization
Publication Title: The FASEB Journal -
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- fsb2fj000288com-fig-0005-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Effects of control connexin mimetic peptide GAP18 on IL‐2 (A), IFNγ (B), and IL‐10 (C) by PHA‐L stimulated mixed populations of T and B lymphocytes. Curves represent (♦) control (no peptide) and...
Article Title: Immunoglobulin and cytokine expression in mixed lymphocyte cultures is reduced by disruption of gap junction intercellular communication
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj010309fje-fig-0004-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description The suppressive effect of AFMK on lipid peroxidation (MDA + 4‐HDA) induced by H2O2 and ferrus iron in rat liver homogenates. The data are expressed as mean ± SE (n=9). *P < 0.05, **P < 0.01 vs. the...
Article Title: N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj000022com-fig-0006-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Tissue localization of β‐Gal activity after injection of anti‐PECAM/SA‐β‐Gal. Conjugates of anti‐PECAM/SA‐β‐Gal or IgG/SA‐β‐Gal (50 µg SA‐β‐Gal/mouse) were injected into tail veins. Organs were...
Article Title: Cell‐selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj010537fje-fig-0001-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description FKBP‐HGFR and FKBP‐HGFR‐K− expression and activation. A) MLP29 cells were infected with retroviral vectors encoding FKBP‐HGFR or FKBP‐HGFR‐K− and selected for stable expression. Cell lysates were...
Article Title: A differentiation switch for genetically modified hepatocytes
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj055460rev-fig-0001-m
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- Rights Managed
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- John Wiley & Sons, Inc.
Description Bidirectional signaling activated by the interaction between Thy‐1 on neurons and integrin β3 on astrocytes. After an interaction between integrin β3 and Thy‐1, FAK, p130Cas, vinculin, paxillin,...
Article Title: Thy‐1 as a regulator of cell‐cell and cell‐matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10155614-fig-0001-m
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- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Overall structure of the Ca2+CaM/SPC complex. A) Side view shows SPC1 and SPC2 bound in quasi‐symmetry‐related positions occupying the hydrophobic pockets of CaM. B) Top view shows the 4 SPC...
Article Title: Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid‐protein interactions
Publication Title: The FASEB Journal -
- Identifier
- fsb2fasebj139002s181-fig-0001-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description At the meetings of the Cell Biology Study Section, Dale Coman had the habit of sketching wild animals on his notepad. Here is his rendition of a hawk.
Article Title: Origins of cell biology in the United States
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj067269com-fig-0001
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- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description HPLC traces of unphosphorylated (A) and PKA phosphorylated FXYD154_72 for1h(B) and 1.5 h (C). Dot blots of 1 ml HPLC fractions collected at 21 and 19.5 min from each of the HPLC traces (see...
Article Title: The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase
Publication Title: The FASEB Journal -
- Identifier
- fsb2fasebj16110169-fig-0008-m
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- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Effect of protein kinase C (PKC) isozyme overexpression on BK‐induced transcriptional activation of COX‐2. Confluent HASM cells (50–60%) were cotransfected with 0.4 μg/well phPES2 (–1432/+59)...
Article Title: Protein kinase C‐ε mediates bradykinin‐induced cyclooxygenase‐2 expression in human airway smooth muscle cells
Publication Title: The FASEB Journal -
- Identifier
- fsb2fasebj13153-fig-0003-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Stimulation of endothelial sprouting from aortic rings observed with laminin‐1 peptides: A) A‐13, at 0.2 mg/ml; B) A‐10, at 0.2 mg/ml; C) A‐64, at 0.2 mg/ml; D) A‐124, example of a peptide active...
Article Title: Identification of laminin α1 and β1 chain peptides active for endothelial cell adhesion, tube formation, and aortic sprouting
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj054747com-fig-0003-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Influence of local and systemic C3 on postischemic acute renal failure. Mice transplanted with isografts exposed to 30 min CIT had remaining native kidney removed on day 5 post‐transplantation....
Article Title: Local extravascular pool of C3 is a determinant of postischemic acute renal failure
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10159285-fig-0001-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Expression of B4 during lens regeneration. A) Detection of B4 expression by RT‐PCR. Lane 1, C. pyrrhogaster ovary; lane 2, C. pyrrhogaster dorsal iris 10 d after lentectomy; lane 3, N. viridescens...
Article Title: Oocyte‐type linker histone B4 is required for transdifferentiation of somatic cells in vivo
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj07102723-fig-0001-m
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- Rights Holder
- John Wiley & Sons, Inc.
Description Cecal samples were cultured in aerobic (A) and anaerobic (B) environments as described in Materials and Methods. Aerobic bacteria counts went below the detection limit in the groups treated with...
Article Title: Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice
Publication Title: The FASEB Journal -
- Identifier
- fsb2fasebj13131677-fig-0005-m
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- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description 3‐Dimensional plot of signaling by wt‐FGF‐2. The concentration axes (Fo and Ho) are log scales and the proliferation index is plotted on a linear scale. In the absence of heparin (Ho = 0, the front...
Article Title: FGF‐2/fibroblast growth factor receptor/heparin‐like glycosaminoglycan interactions: a compensation model for FGF‐2 signaling
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj990833com_table_T1
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Effects of immobilized 4N1K peptide on the arrest of purified CD4‐ or PHA‐activated T cellsa
Article Title: Integrin‐associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj053864fje-fig-0002-m
- License Type
- Rights Managed
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- John Wiley & Sons, Inc.
Description MT (–/–) mice exhibit enhanced tissue damage, including neutrophil infiltration in the kidney after LPS challenge. WT mice or MT (–/–) mice were injected intraperitoneally with 30 mg/kg body weight...
Article Title: Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide in mice
Publication Title: The FASEB Journal -
- Identifier
- fsb221204-fig-0005
- License Type
- CC-BY-NC-ND
- Rights Holder
- Creative Commons by John Wiley & Sons
Description Sp1 is a key transcription factor of spliceosome regulation and cellular senescence. A, Genes positively or negatively correlated with the commonly regulated 58 spliceosomal genes were selected by...
Article Title: Global spliceosome activity regulates entry into cellular senescence
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj09151142-fig-0001-m
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- John Wiley & Sons, Inc.
Description MDR1 and EGFR mRNA distribution on sucrose density fractionation does not shift toward polysomefree fractions following exposure to different types of cellular stress. NCI/ ADR‐RES cells were...
Article Title: mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum
Publication Title: The FASEB Journal -
- Identifier
- fsb2fasebj123325_table_T1
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Effect of P8720 on liver and spleen inflammation and hematological parameters accompanying chronic intestinal inflammation in Lewis ratsa
Article Title: Specific inhibition of plasma kallikrein modulates chronic granulomatous intestinal and systemic inflammation in genetically susceptible rats
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj055500fje-fig-0005
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Maspin can override the inhibiting effect of anti‐β1 integrin. MCF‐10A cells were harvested and preincubated with indicated recombinant proteins. Anti‐MHC I (4) or anti‐β1 integrin (5) were...
Article Title: Maspin is physically associated with β1 integrin regulating cell adhesion in mammary epithelial cellsMaspin is physically associated with β1 integrin regulating cell adhesion in mammary epithelial cells
Publication Title: The FASEB JournalThe FASEB Journal -
- Identifier
- fsb2fj08120345-fig-0004-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Determination of antigen and activity of MMP‐2 in apoE–/– mice and PKCβ–/–/apoE–/– mice. A, B) Antigen level or activity of MMP‐2 from aortic tissue in apoE–/– male mice was determined by Western...
Article Title: Mice deficient in PKC β and apolipoprotein E display decreased atherosclerosis
Publication Title: The FASEB Journal