Description CRAMP is involved in alcohol‐induced IL‐1β production and inflammasome activation. (A) Serum concentrations of IL‐1β. (B) Serum endotoxin levels (left panel) and hepatic mRNA levels of Lbp, Cd14,...
Article Title: Cathelicidin‐related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation
Publication Title: The Journal of Pathology

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Description MALDI imaging of primary colon cancer tissue specimens. (A) Average spectra of UICC II (blue) and UICC III (orange) patient tissue samples. Asterisks indicate significantly differentially expressed...
Article Title: Tissue‐based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer
Publication Title: The Journal of Pathology

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Description Cancer cell fractions (CCFs) of private, shared (by two, three or four tumour components), and ubiquitous mutations (shared by all samples) for the PDTC and ATC primary tumour samples. The private...
Article Title: Whole‐genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation
Publication Title: The Journal of Pathology

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Description Univariate and multivariate Cox regression analyses of DFS
Article Title: Decoding transcriptomic intra‐tumour heterogeneity to guide personalised medicine in ovarian cancer
Publication Title: The Journal of Pathology

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Description Model performance as a function of Pthreshold. (A) Average error rates plotted as a function of Pthreshold. Delaunay triangulation (DT) models were generated using an inclusion criterion of 200...
Article Title: Computational augmentation of neoplastic endometrial glands in digital pathology displays
Publication Title: The Journal of Pathology

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Description Peritoneal macrophages (Mϕs) increased after intraperitoneal administration of sodium hypochlorite. (A) Experimental schema for lineage labeling and analysis in Csf1r‐CreEsr1Tg;Rs26fstdTomato/+...
Article Title: Inflammatory macrophages switch to CCL17‐expressing phenotype and promote peritoneal fibrosis
Publication Title: The Journal of Pathology

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Description CD71− Ter119hi EBs in Fbxo7LacZ/LacZ mice have increased numbers of cells with greater than 2 N DNA content and less p27. (A) Percentage of cells with greater than 2 N DNA content using propidium...
Article Title: Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression
Publication Title: The Journal of Pathology

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Description CRAMP peptide administration rescues alcohol‐induced liver steatosis and injury. Mice were treated as described in the Materials and methods section. (A) Illustration of feeding and treatment...
Article Title: Cathelicidin‐related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation
Publication Title: The Journal of Pathology

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Description Characterization of AP+ muscle fibres, which were found only in pathological muscle biopsies. (A, A′) An AP+ fibre in a biopsy from a Duchenne muscular dystrophy that was positive for NCAM. (B, B′)...
Article Title: The increase of pericyte population in human neuromuscular disorders supports their role in muscle regeneration in vivo
Publication Title: The Journal of Pathology

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Description Schematic diagram of how the recently developed models of endometriosis in mice can be applied to the study of progression to clear cell carcinoma.
Article Title: Models of endometriosis and their utility in studying progression to ovarian clear cell carcinoma
Publication Title: The Journal of Pathology

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Description Pathological post‐mortem findings in lungs infected with SARS‐CoV‐2Autopsy lung findings in SARS‐CoV‐2 patientsS Damiani et al - The Journal of PathologyJ. Pathol. vol. 253, January 2021
Article Title: Pathological post‐mortem findings in lungs infected with SARS‐CoV‐2
Publication Title: The Journal of Pathology

Description Overexpression of FOXM1 impairs differentiation in spheroid cultures of HNSCC cells. (A) Immunoblotting analysis of differentiation markers upon ectopic FOXM1 overexpression in a series of HNSCC...
Article Title: The transcription factor FOXM1 regulates the balance between proliferation and aberrant differentiation in head and neck squamous cell carcinoma
Publication Title: The Journal of Pathology

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Description LC3A SLS are associated with poor patient prognosis in clear cell ovarian carcinoma. Kaplan–Meier analyses of survival in ovarian clear cell carcinoma patients: (A) progression‐free survival; (B)...
Article Title: The autophagy protein LC3A correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer
Publication Title: The Journal of Pathology

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Description Pathological parameters analyzed. (A) TRG in colorectal liver metastases (H&E). TRG 1 (complete response to the treatment with maximal fibrosis); TRG 2 (major response with only scattered...
Article Title: Prognostic assessment of resected colorectal liver metastases integrating pathological features, RAS mutation and Immunoscore
Publication Title: The Journal of Pathology: Clinical Research

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Description The damaging impact of a pathogenic mutation on the properties and functions of the CCT5 molecule
Article Title: Molecular mechanisms in chaperonopathies: clues to understanding the histopathological abnormalities and developing novel therapies
Publication Title: The Journal of Pathology

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Description Detection of the MYB–NFIB fusion gene and MYB and NFIB expression in breast AdCCs. (A), Representative FISH micrographs and results of RT–PCR. A MYB dual‐colour break‐apart probe (top panel) was...
Article Title: Genomic landscape of adenoid cystic carcinoma of the breast
Publication Title: The Journal of Pathology

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Description Inverse correlation between miR‐194 and PTBP1 levels in HCC. (A) Levels of miR‐194 in HCC tissues obtained from three different GEO datasets (GSE 20569, GSE 10694, and GSE 30297). The quantities of...
Article Title: A miR‐194/PTBP1/CCND3 axis regulates tumor growth in human hepatocellular carcinoma
Publication Title: The Journal of Pathology

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Description Analysis of vCJD prions in CSF samples versus non‐CJD controls by hsPMCA. Twenty three CSF samples including cases of other neurodegenerative diseases (Other–ND), non‐neurodegenerative diseases...
Article Title: Rapid amplification of prions from variant Creutzfeldt–Jakob disease cerebrospinal fluid
Publication Title: The Journal of Pathology: Clinical Research

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Description Evolution of structural variations and mutational signatures. (A) Circos plots representing STVs detected in each sample of case 2 are drawn at each node of the schematic tree. STVs common to three...
Article Title: Multiregional whole‐genome sequencing of hepatocellular carcinoma with nodule‐in‐nodule appearance reveals stepwise cancer evolution
Publication Title: The Journal of Pathology

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Description Schematic representation of synthetic lethality exploited by PARP inhibition in the treatment of hereditary BRCA‐related malignancies. DNA repair processes are represented by interlocking...
Article Title: The impact of germline mutations on targeted therapy
Publication Title: The Journal of Pathology

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Description Peritoneal InfMϕs switched to an M2‐biased phenotype after injury. InfMϕs were isolated by FACS before (day 0, only MHC‐II+ Mϕs) and at days 2–7 after peritoneal hypochlorite injury. The results of...
Article Title: Inflammatory macrophages switch to CCL17‐expressing phenotype and promote peritoneal fibrosis
Publication Title: The Journal of Pathology

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Description Table
Article Title: Prognostic assessment of resected colorectal liver metastases integrating pathological features, RAS mutation and Immunoscore
Publication Title: The Journal of Pathology: Clinical Research

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Description The protective effect of fibroblast growth factor‐21 in alcoholic cardiomyopathy: a role in protecting cardiac mitochondrial functionFGF21 and alcoholic cardiomyopathyG Ferrer‐Curriu, M...
Article Title: The protective effect of fibroblast growth factor‐21 in alcoholic cardiomyopathy: a role in protecting cardiac mitochondrial function
Publication Title: The Journal of Pathology

Description Expression and localization of Ccnd1 in GBMs. (A) Representative Ccnd1 staining of glioma samples from the TMA. (B) Boxplot representing the proportion of Ccnd1‐positive cells from samples of...
Article Title: Cytoplasmic cyclin D1 regulates glioblastoma dissemination
Publication Title: The Journal of Pathology

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Description (A) Representative immunohistochemical expression of the markers utilized in the selection of cases for high‐throughput analysis. Bar charts adjacent to each marker describe the dichotomized...
Article Title: A gene signature associated with PTEN activation defines good prognosis intermediate risk prostate cancer cases
Publication Title: The Journal of Pathology: Clinical Research

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Description CD109 expression correlates with the prognosis of patients with WHO grade II/III gliomas. (A) Primary structure of CD109. CD109 is a GPI‐anchored membrane protein that has a unique α2‐macroglobulin...
Article Title: Significance of perivascular tumour cells defined by CD109 expression in progression of glioma
Publication Title: The Journal of Pathology

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Description PGC‐1α downregulation promotes cell death and sensitizes to TWEAK‐induced proinflammatory responses in tubular cells. Murine proximal tubular MCT cells were infected with adenoviruses expressing...
Article Title: PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI
Publication Title: The Journal of Pathology

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Description Ras‐Raf activation induces epidermal hyperplasia during postnatal development. (A) HrasS35epTg mice, which express an effector mutant H‐RasS35 in the epidermis. Western blots show that...
Article Title: CBP/p300 antagonises EGFR‐Ras‐Erk signalling and suppresses increased Ras‐Erk signalling‐induced tumour formation in mice
Publication Title: The Journal of Pathology

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Description T2D increases Ly6Chi Mo numbers in the circulation and spleen and Mo/Mp in the wounds of DB mice following skin wounding. (A–C) BM, circulating and splenic Ly6Chi Mo; (A) percentage (of total...
Article Title: Diabetes induces myeloid bias in bone marrow progenitors associated with enhanced wound macrophage accumulation and impaired healing
Publication Title: The Journal of Pathology

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Description Differentially expressed proteins between the resistant (RES) clone C475 and the sensitive (SENS) clone C271
Article Title: Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity
Publication Title: The Journal of Pathology

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