Asset Details
- Identifier:
- tox23036-fig-0004
- Description:
- SNCG is a downstream target gene of miR‐497‐5p. (A) The potential downstream target genes of miR‐497‐5p were speculated by starBase website and the venn diagram was shown. (B) The relative expressions of potential downstream target genes were detected by RT‐qPCR in miR‐497‐5p mimics transfected cells. (C) SNCG expression was evaluated by RT‐qPCR in normal prostate cell line WPMY1 and PCa cell lines (LNCap, DU145, PC‐3 and VCap). (D) The potential binding site between miR‐497‐5p and SNCG was predicted by starBase website and proved by luciferase reporter assay. (E) RIP assay was conducted to evaluate the enrichment degrees of miR‐497‐5p and SNCG in Ago2 or IgG immunoprecipitation. (F) The mRNA and protein level of SNCG were measured by RT‐qPCR and western blot analyses, respectively. *P < .05, **P < .01 [Color figure can be viewed at wileyonlinelibrary.com]
- License:
- Rights Managed
- Rights Holder:
- John Wiley & Sons, Inc.
- License Rights Holder:
- © 2021 Wiley Periodicals LLC.
- Asset Type:
- Image
- Asset Subtype:
- Image Orientation:
- Portrait
- Image Dimensions:
- 2128 x 3000
- Image File Size:
- 1.49 MB
- Creator:
- Xu Zhu, Xingxin Ma, Shuli Zhao, Zhigang Cao
- Credit:
- Zhu, X., Ma, X., Zhao, S., & Cao, Z. (2021). DLX6‐AS1 accelerates cell proliferation through regulating miR‐497‐5p/SNCG pathway in prostate cancer. Environmental Toxicology, 36(3), 308-319. https://doi.org/10.1002/tox.23036.
- Collection:
- Keywords:
- Restrictions:
- Property Release:
- No
- Model Release:
- No
- Purchasable:
- Yes
- Sensitive Materials:
- No
- Article Title:
- DLX6‐AS1 accelerates cell proliferation through regulating miR‐497‐5p/SNCG pathway in prostate cancer
- Article Authors:
- Xu Zhu, Xingxin Ma, Shuli Zhao, Zhigang Cao
- Article Copyright Year:
- 2021
- Publication Title:
- Environmental Toxicology
- Publication Volume:
- 36
- Publication Issue:
- 3
- Publication Date:
- 03/01/2021
- DOI:
- https://doi.org/10.1002/tox.23036
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