• Identifier:
• IMR_726_f2

• Description:
• Hypothetical model of functional diversity among viral sensors. Three potential mechanisms by which viral sensors perform unique functions: (i) viral sensors detect different ligands resulting in the recognition of a variety of viral families and/or the recognition of different components of the same virus. (ii) Toll‐like receptor (TLR) and retinoic acid‐inducible gene I‐like receptor (RLR) signaling results in the production of different cytokine responses (i.e. type I interferon versus pro‐inflammatory cytokines). (iii) The expression of TLRs and RLRs in different cell types results in unique responses to viruses in different cells and tissues. Predominant sensors are indicated in bold, while secondary sensors are indicated below in smaller font.

• License:
• Rights Managed

• Rights Holder:
• John Wiley & Sons, Inc.

• License Rights Holder:
• © 2009 The Authors Journal compilation © 2009 Blackwell Munksgaard

• Asset Type:
• Image

• Asset Subtype:
• Chart/Graph

• Image Orientation:
• Landscape

• Image Dimensions:
• x

• Image File Size:
• 15.3 KB

• Creator:
• Stephen A. McCartney, Marco Colonna

• Credit:
• McCartney, S. A., & Colonna, M. (2009). Viral sensors: diversity in pathogen recognition. Immunological Reviews, 227(1), 87-94. https://doi.org/10.1111/j.1600-065X.2008.00726.x.

• Collection:

• Keywords:

• Restrictions:

• Property Release:
• No

• Model Release:
• No

• Purchasable:
• No

• Sensitive Materials:
• No

• Article Title:
• Viral sensors: diversity in pathogen recognition

• Article Authors:
• Stephen A. McCartney, Marco Colonna

• Article Copyright Year:
• 2009

• Publication Title:
• Immunological Reviews

• Publication Volume:
• 227

• Publication Issue:
• 1

• Publication Date:
• 01/01/2009

• DOI:
• https://doi.org/10.1111/j.1600-065X.2008.00726.x