Advanced Search
Displaying assets from 1 to 30 out of 7
-
Description In vivo antibacterial efficacy of IK8L in a mouse MDR P. aeruginosa 118‐induced burn wound infection model. A) Reduction of viable bacterial colonies in mice skin specimens taken on the 2nd and 3rd...
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials -
Description Membrane‐lytic mechanism of IK8L. TEM images of P. aeruginosa 118 A,C) before and B,D) after treatment with IK8L for 1 h at 37 °C. Size of the scale bar: 1 µm for (A) and (B) and 0.2 µm for (C) and...
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials -
Description In vitro bacteria resistance studies. P. aeruginosa 118 was serially passaged together with IK8L, levofloxacin, ceftazidime, and imipenem at subtherapeutic concentrations for up to ten passages....
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials -
Description Antibiofilm activity of IK8L. A) Cell viability and B) biomass of P. aeruginosa 118 biofilm after peptide treatment for 24 h at various concentrations.
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials -
Description In vitro killing kinetics of IK8L, ceftazidime, and imipenem. CFUs of P. aeruginosa 118 from the different treatment arms were compared at varying concentrations A) 1× MIC, B) 2× MIC, and C) 4×...
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials -
Description Viability of human HaCaT keratinocytes after incubation with the peptides or polymyxin B for 16 h at 37 °C.
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials -
Description Confocal microscopic images of P. aeruginosa 118 incubated with FITC‐conjugated dextran (100 kDa, 250 µg mL−1) in the presence of A) PBS or B) IK8L for 1 h. A1,B1) Green represents fluorescence of...
Article Title: Short Synthetic β‐Sheet Antimicrobial Peptides for the Treatment of Multidrug‐Resistant Pseudomonas aeruginosa Burn Wound Infections
Publication Title: Advanced Healthcare Materials