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Description Effects of pretreatment with OEA in the HMGB1/TLR4 signaling pathway activated by ethanol binge exposure in frontal cortex. a) HMGB1 levels measured by enzyme‐linked immunosorbent assays; b) HMGB1...
Article Title: Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF‐kB danger signaling in rat frontal cortex and depressive‐like behavior induced by ethanol binge administration
Publication Title: Addiction Biology -
Description Depiction of the direction of interaction effects between early‐life stress and ethanol drinking on gene expression in MS rats, assessed with the Univariate General Linear Model (GLM) test, two‐way...
Article Title: Ethanol affects limbic and striatal presynaptic glutamatergic and DNA methylation gene expression in outbred rats exposed to early‐life stress
Publication Title: Addiction Biology -
Description Correlations with craving during smoking cue exposure relative to non‐smoking cue exposure.
Article Title: Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort
Publication Title: Addiction Biology -
Description EtOH_Ind and EtOH_Cpa mice have diminished number of proliferative/survivors cells in relation to Control and EtOH_Cpp groups. (a) Total number of BrdU+ cells per mm2. The data are expressed as...
Article Title: Effects of ethanol on hippocampal neurogenesis depend on the conditioned appetitive response
Publication Title: Addiction Biology -
Description Group differences in brain response during anticipation of monetary loss (contrast: loss cue > neutral cue, corrected for local gray matter volume, age, smoking and BDI‐II scores). Group...
Article Title: Pathological gambling and alcohol dependence: neural disturbances in reward and loss avoidance processing
Publication Title: Addiction Biology -
Description Ethanol‐induced hypothermia is modulated by Per2. At Zeitgeber time (ZT) 5, an acute challenge of ethanol (3.5 g/kg, intraperitoneal) resulted in less hypothermia in Per2Brdm1 mutant mice compared...
Article Title: PRECLINICAL STUDY: Circadian regulation of central ethanol sensitivity by the mPer2 gene
Publication Title: Addiction Biology -
Description Subject characteristics
Article Title: Dopamine and serotonin genetic risk scores predicting substance and nicotine use in attention deficit/hyperactivity disorder
Publication Title: Addiction Biology -
Description HRV parameters for subgroups of METH participants differentiated by the lifetime quantity of METH use (a), length of abstinence (b), and number of days of METH use in the past year (c).
Article Title: Effect of methamphetamine dependence on heart rate variability
Publication Title: Addiction Biology -
Description N‐acetylcysteine (NAC), aspirin (ASA), or co administration of NAC + ASA during the alcohol deprivation period (shaded area) after chronic alcohol consumption markedly inhibited relapse drinking...
Article Title: Aspirin and N‐acetylcysteine co‐administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation‐oxidative stress self‐perpetuation
Publication Title: Addiction Biology -
Description No difference in basal CeA IPSPs between naïve/sham and chronic morphine‐treated rats. We implanted 2 placebo or morphine pellets s.c and performed intracellular recording on day 6 after the pellet...
Article Title: Neuroadaptation of GABAergic transmission in the central amygdala during chronic morphine treatment
Publication Title: Addiction Biology -
Description Nicotine depresses the excitability of medium spiny neurons (MSNs) in the shell of the nucleus accumbens (ShNAc). (a) Superimposed traces acquired from a digital storage oscilloscope showing a...
Article Title: PRECLINICAL STUDY: FULL ARTICLE: Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR‐α nuclear receptors
Publication Title: Addiction Biology -
Description Influence of naltrexone (NTX; 3.0 mg/kg) alone on conditioned place preference.
Article Title: PRECLINICAL STUDY: The effect of naltrexone on amphetamine‐induced conditioned place preference and locomotor behaviour in the rat
Publication Title: Addiction Biology -
Description Repeated measures ANOVA for longitudinal behavioural data (N = 92 adolescents).
Article Title: Low‐level alcohol consumption during adolescence and its impact on cognitive control development
Publication Title: Addiction Biology -
Description Ethanol intakes during the first two hours of access following a deprivation period by high‐alcohol‐drinking‐1 (HAD‐1) and HAD‐2 rats, initially deprived for 8 weeks and then exposed to repeated...
Article Title: PRECLINICAL STUDY: Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of high‐alcohol‐drinking (HAD) rats
Publication Title: Addiction Biology -
Description Prediction of biological indicators of stress from previous traumatic events reported at baseline.
Article Title: Biological stress indicators as risk markers for increased alcohol use following traumatic experiences
Publication Title: Addiction Biology -
Description Statistical parametric mapping map of blood oxygen level‐dependent response to cocaine cues minus neutral objects in untreated versus treated participants using a voxelwise threshold of z = 2.33...
Article Title: Brain activation to cocaine cues and motivation/treatment status
Publication Title: Addiction Biology -
Description Mean peak ratings of estimated street value (left panel), participant‐ (middle panel) and observer‐rated (right panel) opioid agonist ratings, presented as a function of dose [n = 9; ±1 standard...
Article Title: Pharmacodynamic effects of oral oxymorphone: abuse liability, analgesic profile and direct physiologic effects in humans
Publication Title: Addiction Biology -
Description TABLE
Article Title: Alcohol consumption is associated with widespread changes in blood DNA methylation: Analysis of cross‐sectional and longitudinal data
Publication Title: Addiction Biology -
Description Mice made abstinent from morphine, nicotine, THC, alcohol but not cocaine show social interaction deficit, motor stereotypies and increased marble burying. (A) Social interaction test performed...
Article Title: Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol
Publication Title: Addiction Biology -
Description Verification of the in vivo transduction efficacy of the adeno‐associated viruses (AAVs) constructs within vmPFC. (a) Micrograph (4× magnification of tissue section) of immunofluorescence for the...
Article Title: Cocaine‐elicited imbalances in ventromedial prefrontal cortex Homer1 versus Homer2 expression: implications for relapse
Publication Title: Addiction Biology -
Description Spontaneous open‐field locomotor activity (mean ± SE of number of squares crossed) presented by mice acutely treated with vehicle (Veh), 0.5 mg/kg haloperidol (Hal) or 0.5 mg/kg risperidone (Ris)....
Article Title: PRECLINICAL STUDY: Long‐term haloperidol treatment (but not risperidone) enhances addiction‐related behaviors in mice: role of dopamine D2 receptors
Publication Title: Addiction Biology -
Description The subnetwork derived from the network‐based statistic (NBS) analysis. (a) Increased structural connections in heroin‐dependent individuals (HDIs). These connections formed a single subnetwork...
Article Title: Abnormal white matter structural networks characterize heroin‐dependent individuals: a network analysis
Publication Title: Addiction Biology -
Description Cerebellar structure and chronic drug exposure
Article Title: The cerebellum and addiction: insights gained from neuroimaging research
Publication Title: Addiction Biology -
Description TABLE
Article Title: Heritability of tea drinking and its relationship with cigarette smoking in the Chinese male adult twins
Publication Title: Addiction Biology -
Description Effects of MFZ 10‐7 and MTEP on cocaine‐induced reinstatement of drug‐seeking behavior. Pretreatment with MFZ 10‐7 (0, 3 or 10 mg/kg, i.p.) (a) or MTEP (0, 1 or 10 mg/kg, i.p.) (b) dose‐dependently...
Article Title: A novel mGluR5 antagonist, MFZ 10‐7, inhibits cocaine‐taking and cocaine‐seeking behavior in rats
Publication Title: Addiction Biology -
Description Coronal diagrams of the rat brain showing the location of the tips of the biosensor in the BLA (a) and NAc core (b). Biosensor placement was determined from postmortem histological analysis of...
Article Title: Alcohol‐seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate‐oxidase‐coated biosensors
Publication Title: Addiction Biology -
Description Effect of dopaminergic antagonists on hyperlocomotion in mice. (a–b) In buphedrone‐induced hyperlocomotion, mice were pre‐treated with either SCH23390 (0.5 mg/kg; SCH) or raclopride (1 mg/kg; RAC)...
Article Title: The new designer drug buphedrone produces rewarding properties via dopamine D1 receptor activation
Publication Title: Addiction Biology -
Description The experimental time‐line and schedule of intra‐ventral tegmental area (VTA) micro‐infusions during cocaine seeking and sucrose seeking under extinction conditions. (a) Rats, after intravenous...
Article Title: Noradrenergic signaling in the VTA modulates cocaine craving
Publication Title: Addiction Biology -
Description Mitochondrial and apoptotic parameters in newborn CBMC. CBMC = cord blood mononuclear cells; COX = cytochrome c oxidase; mtDNA = mitochondrial DNA; CS = citrate synthase; VDAC1 = voltage‐dependent...
Article Title: Molecular basis of reduced birth weight in smoking pregnant women: mitochondrial dysfunction and apoptosis
Publication Title: Addiction Biology -
Description Gαi inhibition abolishes quinpirole‐mediated inhibition of MSN spike excitability in control mice, but has no effect in Dbh −/− mice. Example traces from MSNs recorded from a control (a) and a Dbh...
Article Title: Chronic loss of noradrenergic tone produces β‐arrestin2‐mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens
Publication Title: Addiction Biology