• Identifier:
• embj7594215-fig-0006

• Description:
• A possible mechanism for regulation of competition between the RF2 and Sec‐tRNASec decoding molecules at the fdhF selenocysteine insertion site. (A) A kinetic scheme of the competition between the decoding molecules, RF2 and Sec‐tRNASec, at the rsUGA. k1 and k2 represent the rate of Sec‐tRNASec and RF2 association, respectively. (B) The ‘helical approach’ model for competitive delivery of Sec‐tRNASec to the rsUGA. (1) The SELB complex carrying the Sec‐tRNASec is bound to the apical tip of the fdhF stem–loop as the sequence approaches the ribosomal decoding site. (2) The ribosomal melting impetus (triangle) encounters the stem–loop and induces unwinding. (3) The SELB complex is positioned towards the ribosomal SELB‐binding site (RSB) allowing proximity and delivery of Sec‐tRNASec to the ribosomal A site in competition with RF2.

• License:
• Rights Managed

• Rights Holder:
• John Wiley & Sons, Inc.

• License Rights Holder:
• Copyright © 2013 Wiley Periodicals, Inc

• Asset Type:
• Image

• Asset Subtype:
• Figure

• Image Orientation:
• Portrait

• Image Dimensions:
• 251 x 640

• Image File Size:
• 26.2 KB

• Creator:
• John B. Mansell, Diane Guévremont, Elizabeth S. Poole, Warren P. Tate

• Credit:
• Mansell, J. B., Guévremont, D., Poole, E. S., & Tate, W. P. (2001). A dynamic competition between release factor 2 and the tRNASec decoding UGA at the recoding site of Escherichia coli formate dehydrogenase H. The EMBO Journal, 20(24), 7284-7293..

• Collection:

• Keywords:

• Restrictions:

• Property Release:
• No

• Model Release:
• No

• Purchasable:
• No

• Sensitive Materials:
• No

• Article Title:
• A dynamic competition between release factor 2 and the tRNASec decoding UGA at the recoding site of Escherichia coli formate dehydrogenase H

• Article Authors:
• John B. Mansell, Diane Guévremont, Elizabeth S. Poole, Warren P. Tate

• Article Copyright Year:
• 2001

• Publication Title:
• The EMBO Journal

• Publication Volume:
• 20

• Publication Issue:
• 24

• Publication Date:
• 12/17/2001

• DOI: