Asset Details

  • Description:
  • Knockdown of ventral tegmental area (VTA) glial cell line‐derived neurotrophic factor (GDNF) facilitates ethanol drinking escalation by ethanol‐naïve rats. Recombinant adenoviruses containing small hairpin RNA (shRNA) targeting GDNF (shGDNF; black squares) or a scrambled control sequence (SCR; white squares) were bilaterally infused into the VTA of rats. Ethanol (a) and water (b) consumption in the intermittent access to 20% ethanol two‐bottle choice paradigm was measured beginning 10 days after the virus infusion. Graph represents amount of ethanol (a) or water (b) consumed ± SEM, n = 9 per group. **P < 0.01, as compared with the SCR control group
  • License:
  • Rights Managed
  • Rights Holder:
  • John Wiley & Sons, Inc.
  • License Rights Holder:
  • © 2014 Society for the Study of Addiction
  • Asset Type:
  • Image
  • Asset Subtype:
  • Chart/Graph
  • Image Orientation:
  • Portrait
  • Image Dimensions:
  • 590 x 1022
  • Image File Size:
  • 154 KB
  • Creator:
  • Somayeh Ahmadiantehrani, Segev Barak, Dorit Ron
  • Credit:
  • Ahmadiantehrani, S., Barak, S., & Ron, D. (2014). GDNF is a novel ethanol‐responsive gene in the VTA: implications for the development and persistence of excessive drinking. Addiction Biology, 19(4), 623-633..
  • Collection:
  • Keywords:
  • Restrictions:
  • Property Release:
  • No
  • Model Release:
  • No
  • Purchasable:
  • Yes
  • Sensitive Materials:
  • No
  • Article Authors:
  • Somayeh Ahmadiantehrani, Segev Barak, Dorit Ron
  • Article Copyright Year:
  • 2014
  • Publication Volume:
  • 19
  • Publication Issue:
  • 4
  • Publication Date:
  • 07/01/2014
  • DOI:

Click on image to enlarge

Would you like to download this asset? Tell us more and we can generate a quote, license and downloadable file.

Add to Cart