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Displaying assets from 1 to 30 out of 8
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- Identifier
- fsb2fj10169789-fig-0003-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Endothelial endocytosis and endosomal delivery of anti‐PECAM/SOD. A) Binding and uptake of anti‐PECAM/SOD. Cells were treated with anti‐PECAM/SOD for 1 h, washed, fixed, stained with Alexa Fluor...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789-fig-0004-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Pulmonary localization of anti‐PECAM/SOD in vivo. Anesthetized mice were injected intravenously with 150 µgof anti‐PECAM/SOD or control IgG/SOD. At 1 h postinjection, lungs were harvested and...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789-fig-0005-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Anti‐PECAM/SOD inhibits elevation of pulmonary VCAM in LPS‐challenged animals. Anti‐PECAM/SOD or PEG‐modified enzymes were injected in tail vein followed by LPS challenge (50 µg/kg). After 5 h,...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789-fig-0001-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Kinetics of endothelial cell activation by proinflammatory agents. A‐C) HUVECs were treated with TNF (10 ng/ml; A), IL‐1β (10 ng/ml; B), or LPS (0.5 µg/ml; C) for indicated times, and samples were...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789_table_T1
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description PECAM‐1‐targeted pulmonary accumulation of antioxidant enzymes after i.v. injection in mice
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789-fig-0006-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Mechanism of anti‐inflammatory effects of anti‐PECAM/SOD. A) Anti‐PECAM/SOD, but not naked SOD, quenches endosomal superoxide. Endothelial cells were pretreated with membrane nonpermeable dye...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789-fig-0007-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Anti‐PECAM/SOD blocks TLR3‐mediated endothelial cell activation by poly(I:C). A) Effect of antioxidant enzymes on poly(I:C) activation of VCAM protein level determined by Western blotting. B)...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal -
- Identifier
- fsb2fj10169789-fig-0002-m
- License Type
- Rights Managed
- Rights Holder
- John Wiley & Sons, Inc.
Description Anti‐PECAM/SOD inhibits VCAM expression in endothelial cells activated by cytokines and LPS. A, B) Confluent human endothelial cells were treated with native SOD or catalase vs. anti‐PECAM/SOD or...
Article Title: PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response
Publication Title: The FASEB Journal
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